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Isolation and characterization of an unsaturated fatty acid-requiring mutant of cultured mammalian cells

Proceedings of the National Academy of Sciences of the United States of America

Jan 1, 1976

T Y Chang, P R Vagelos

PMID: 1750

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Abstract

An unsaturated fatty acid-requiring mutant derived from Chinese hamster ovary (CHO) cells has been isolated and characterized. This mutant grows normally when oleate or other unsaturated fatty acids are supplemented in the growth medium. Unlike the wild-type CHO cells, growth stops when...read more

Mentioned in this Paper

Oleic Acids
SCD gene
Stearoyl-CoA Desaturase
Thyroid Hormone Plasma Membrane Transport Defect
Entire Ovary
Mutant
Plasma Membrane
Stearate
Ovary
Oleates
Paper Details
References
    • References12
    • Citations10
    • References12
    • Citations10
  • Isolation and characterization of an unsaturated fatty acid-requiring mutant of cultured mammalian cells

    Proceedings of the National Academy of Sciences of the United States of America

    Jan 1, 1976

    T Y Chang, P R Vagelos

    PMID: 1750

    DOI:

    Abstract

    An unsaturated fatty acid-requiring mutant derived from Chinese hamster ovary (CHO) cells has been isolated and characterized. This mutant grows normally when oleate or other unsaturated fatty acids are supplemented in the growth medium. Unlike the wild-type CHO cells, growth stops when...read more

    Mentioned in this Paper

    Oleic Acids
    SCD gene
    Stearoyl-CoA Desaturase
    Thyroid Hormone Plasma Membrane Transport Defect
    Entire Ovary

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    Paper Details
    References
    • References12
    • Citations10
    • References12
    • Citations10
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