Isolation and Characterization of Strain MMB-1 (CECT 4803), a Novel Melanogenic Marine Bacterium.

Applied and Environmental Microbiology
F SolanoAntonio Sanchez-Amat

Abstract

A novel marine melanogenic bacterium, strain MMB-1, was isolated from the Mediterranean Sea. The taxonomic characterization of this strain indicated that it belongs to the genus Alteromonas. Under in vivo conditions, L-tyrosine was the specific monophenolic precursor for melanin synthesis. This bacterium contained all types of activities associated with polyphenol oxidases (PPOs), cresolase (EC 1.18.14.1), catecholase (EC 1.10.3.1), and laccase (EC 1.10.3.2). These activities were due to the presence of two different PPOs. The first one showed all the enzymatic activities, but it was not involved in melanogenesis in vivo, since amelanogenic mutant strains obtained by nitrosoguanidine treatment contained levels of this PPO similar to that of the wild-type MMB-1 strain. The second PPO showed cresolase and catecholase activities but no laccase, and it was involved in melanogenesis, since this enzyme was lost in amelanogenic mutant strains. This PPO was strongly activated by sodium dodecyl sulfate below the critical micelle concentration, and it is a tyrosinase-like enzyme showing a lag period in its tyrosine hydroxylase activity that could be avoided by small amounts of L-dopa. This is the first report of a bacterium that contains...Continue Reading

References

Jan 1, 1974·Archives of Biochemistry and Biophysics·S H Pomerantz, V V Murthy
Dec 18, 1972·European Journal of Biochemistry·K Lerch, L Ettinger
Dec 1, 1993·Pigment Cell Research·C Jimenez-CervantesJ A Lozano
Jun 1, 1995·Pigment Cell Research·C RuzafaF Solano
Mar 1, 1995·Applied and Environmental Microbiology·Y Fukushima, T K Kirk
Jan 1, 1950·Physiological Reviews·A B LERNER, T B FITZPATRICK
Apr 1, 1988·Applied and Environmental Microbiology·G Andrykovitch, I Marx
Sep 1, 1990·Applied and Environmental Microbiology·A Sánchez-Amat, F Torrella
Sep 1, 1994·Applied and Environmental Microbiology·D FaureR Bally
Mar 1, 1995·Applied and Environmental Microbiology·D SlomczynskiS W Tanenbaum
Dec 1, 1996·Applied and Environmental Microbiology·P J CollinsA Dobson

❮ Previous
Next ❯

Citations

Oct 1, 2011·Evidence-based Complementary and Alternative Medicine : ECAM·Azamjon B SolievKeiichi Enomoto
Nov 30, 1999·Pigment Cell Research·E FernándezF Solano
Jun 17, 2003·International Journal of Systematic and Evolutionary Microbiology·Lyudmila A RomanenkoTai Uchimura
Nov 5, 2005·Applied and Environmental Microbiology·Diana Hernández-RomeroAntonio Sanchez-Amat
Apr 5, 2003·Applied and Environmental Microbiology·M Enriqueta AriasManuel Hernández
Oct 30, 2001·FEMS Microbiology Letters·F SolanoA Sanchez-Amat
Oct 3, 2006·International Journal of Systematic and Evolutionary Microbiology·Ken W K LauMadeline Wu
May 15, 2002·FEMS Microbiology Letters·Susana Castro-SowinskiYaacov Okon
Apr 9, 2002·Pigment Cell Research·Daniel López-SerranoFrancisco Solano
Oct 16, 2012·American Journal of Physiology. Gastrointestinal and Liver Physiology·Yasunari AsanoNobuyuki Sudo
Jul 23, 2013·MicrobiologyOpen·Jonatan Cristian Campillo-BrocalAntonio Sanchez-Amat
Apr 22, 2015·Bioscience, Biotechnology, and Biochemistry·Daisuke Matsui, Yasuhisa Asano
Sep 1, 2008·Indian Journal of Microbiology·Krishna Kant Sharma, Ramesh Chander Kuhad
Jul 27, 2010·Applied and Environmental Microbiology·Luisa R Molina-QuinteroAntonio Sanchez-Amat
Jun 8, 2012·Standards in Genomic Sciences·Patricia Lucas-ElíoAntonio Sanchez-Amat
Jan 13, 2015·Cellular and Molecular Life Sciences : CMLS·Lígia O MartinsPeter F Lindley
Aug 21, 2013·Applied Microbiology and Biotechnology·María Dolores Chacón-VerdúAntonio Sánchez-Amat
Sep 29, 2017·3 Biotech·Prakram Singh ChauhanArunika Saxena
Dec 14, 2018·Marine Drugs·Andrés Andreo-VidalJonatan C Campillo-Brocal
Aug 17, 2019·Frontiers in Endocrinology·Nobuyuki Sudo
Aug 16, 2017·Science Advances·Shuaiqi GuoPeter L Davies
Dec 17, 1997·Biochemical and Biophysical Research Communications·A Sanchez-Amat, F Solano
Apr 24, 2004·Journal of Natural Products·M Sanchez-Gonzalez, J P N Rosazza

❮ Previous
Next ❯

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.