PMID: 7547471Jun 1, 1995Paper

Isolation and embryonic expression of Xel-1, a nervous system-specific Xenopus gene related to the elav gene family

Mechanisms of Development
M PerronM Wegnez

Abstract

We have identified a new member of the elav gene family in Xenopus laevis. This gene, Xel-1, like the other elav-related genes, encodes a putative RNA-binding protein that contains three RNA Recognition Motifs and is solely expressed in the nervous system. Xel-1 is most likely the Xenopus homologue of Hel-N1, one of the three known human genes related to elav. Xel-1 is not expressed in early neural precursors but rather in differentiating neurons of the central nervous system, as well as in the cranial and the spinal ganglion cells. Xel-1 thus appears to be an early differentiation marker for both the central and the peripheral nervous system of Xenopus laevis.

References

Dec 1, 1977·Proceedings of the National Academy of Sciences of the United States of America·F SangerA R Coulson
Feb 20, 1992·Nature·S Piñol-Roma, G Dreyfuss
Oct 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·C WechselbergerK Richter
Jan 1, 1991·Progress in Nucleic Acid Research and Molecular Biology·J D Keene, C C Query
Jun 1, 1991·Trends in Biochemical Sciences·D J KenanJ D Keene
Feb 1, 1992·Developmental Biology·M F Marusich, J A Weston
Jan 1, 1991·Methods in Cell Biology·R M Harland
Apr 1, 1989·Genes & Development·R J BandziulisG Dreyfuss
Sep 26, 1988·Nucleic Acids Research·J P DumanskiS Datta
Feb 1, 1994·Journal of Neurobiology·M F MarusichJ A Weston
Dec 1, 1993·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·H H Epperlein, J Löfberg
Mar 1, 1993·Genes & Development·J G PattonB Nadal-Ginard
Nov 1, 1961·The Journal of Experimental Zoology·V HAMBURGER

❮ Previous
Next ❯

Citations

Sep 15, 1997·Nucleic Acids Research·W J MaH Furneaux
Sep 3, 1999·Mechanisms of Development·M PerronL Théodore
May 10, 1996·The Journal of Biological Chemistry·S ChungH Furneaux
Dec 14, 2004·The Journal of Comparative Neurology·Marcos A AmatoMuriel Perron

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.