PMID: 4887228Apr 1, 1969Paper

Isolation and properties of secretory granules from rat islets of Langerhans. II. Ultrastructure of the beta granule

The Journal of Cell Biology
M H GreiderP E Lacy

Abstract

Beta granules isolated from rat islets of Langerhans and subjected only to phosphotungstic acid had, in negatively stained images, a 50-A periodicity. This periodicity was also observed in thin-section profiles of beta granules in intact cells. In shadowed preparations, the granules were spherical in shape and had irregular edges and surface structure. The presence of such a periodicity in the beta granule indicates that its matrix may be composed of a crystalline material.

References

Jan 26, 1967·The New England Journal of Medicine·P E Lacy
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Jan 1, 1973·Acta diabetologica latina·P Petkov, S Donev
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