PMID: 3753968Jan 1, 1986Paper

Isolation and structure of antibiotic U-68,204, a new thiolactone

The Journal of Antibiotics
L A DolakO K Sebek

Abstract

A new thiolactone-containing antibiotic U-68,204 was found to be produced by a soil actinomycete identified as Streptomyces thiolactonus UC 8478 (NRRL 15,439). The production, isolation, structure determination as well as the physical, spectroscopic and antibacterial properties of this C13H17NO3S compound are here reported. On the basis of these data, the antibiotic was identified as the 10-carboxamide of thiotetromycin.

Citations

Jan 1, 1991·Critical Reviews in Biotechnology·C M Franco, L E Coutinho
Sep 7, 2001·Annual Review of Microbiology·J W Campbell, J E Cronan
May 31, 2006·Heterocycles·Gautham ShenoyCynthia S Dowd
Nov 2, 2004·The Journal of Biological Chemistry·Srinivas KodaliJun Wang
Jan 27, 2006·Antimicrobial Agents and Chemotherapy·Katherine YoungJun Wang
Apr 26, 2007·Proceedings of the National Academy of Sciences of the United States of America·Jun WangSheo B Singh
Feb 13, 2007·Bioorganic & Medicinal Chemistry·Yves L Janin
May 26, 2007·Chemistry & Biology·Mamoun M AlhamadshehKevin A Reynolds

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