Isolation of a bioactive Ca(2+)-mobilizing complex lipid from bovine vitreous body

Biochemical and Biophysical Research Communications
J P CamiñaF F Casanueva

Abstract

Vitreous body extracts show a potent Ca(2+)-mobilizing activity on fibroblast cells. This Ca2+ signal is complex, and due to the presence of two different bioactive substances. The first one was identified as acid FGF. The second one was shown to be a low molecular weight substance identified as a complex lipid by a combination of chromatographic and biochemical data. This finding raises the possibility that non-classical substances with growth factor-like activity might play a role in the regulation of proliferative processes in the eye.

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Citations

Jul 3, 2015·PloS One·Vivek Phani VarmaSandeep Goel
Aug 18, 2021·Heliyon·Karthikeyan Subbiahanadar ChelladuraiJohnson Retnaraj Samuel Selvan Christyraj

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