journal cover

Isolation of a shark immunoglobulin light chain cDNA clone encoding a protein resembling mammalian kappa light chains: implications for the evolution of light chains

Proceedings of the National Academy of Sciences of the United States of America

Nov 15, 1993

A S GreenbergMartin F Flajnik

PMID: 8248152

Abstract

The time of emergence of immunoglobulin kappa and lambda light (L) chains in evolution is unknown. An L chain cDNA clone was isolated from the nurse shark (Ginglymostoma cirratum), a cartilaginous fish, whose predicted variable (V) region amino acid sequence has up to 60% sequence ident...read more

Mentioned in this Paper

Immunoglobulin Activity
Genome
Genes, Reiterated
Ginglymostoma cirratum
Homologous Sequences, Amino Acid
Shark - fish
Immunoglobulin Isotypes
Fish <Chondrichthyes>
Phylogeny
Southern Blot Result
19
Paper Details
References
  • References33
  • Citations35
1234
  • References33
  • Citations35
1234

Feeds With Similar Papers

Genetic Speciation

Speciation depends on the genetic evolution of reproductive barriers that allow populations to diverge from each other. Discover the latest research on Genetic Speciation here.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America

Complete nucleotide sequence of primitive vertebrate immunoglobulin light chain genes

Proceedings of the National Academy of Sciences of the United States of AmericaJune 1, 1989
M J Shamblott, G W Litman
© 2020 Meta ULC. All rights reserved

Isolation of a shark immunoglobulin light chain cDNA clone encoding a protein resembling mammalian kappa light chains: implications for the evolution of light chains

Proceedings of the National Academy of Sciences of the United States of America

Nov 15, 1993

A S GreenbergMartin F Flajnik

PMID: 8248152

DOI:

Abstract

The time of emergence of immunoglobulin kappa and lambda light (L) chains in evolution is unknown. An L chain cDNA clone was isolated from the nurse shark (Ginglymostoma cirratum), a cartilaginous fish, whose predicted variable (V) region amino acid sequence has up to 60% sequence ident...read more

Mentioned in this Paper

Immunoglobulin Activity
Genome
Genes, Reiterated
Ginglymostoma cirratum
Homologous Sequences, Amino Acid
Shark - fish
Immunoglobulin Isotypes
Fish <Chondrichthyes>
Phylogeny
Southern Blot Result
19

Feeds With Similar Papers

Genetic Speciation

Speciation depends on the genetic evolution of reproductive barriers that allow populations to diverge from each other. Discover the latest research on Genetic Speciation here.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America

Complete nucleotide sequence of primitive vertebrate immunoglobulin light chain genes

Proceedings of the National Academy of Sciences of the United States of AmericaJune 1, 1989
M J Shamblott, G W Litman
Paper Details
References
  • References33
  • Citations35
1234
  • References33
  • Citations35
1234

Download from

PubMed
/papers/isolation-of-a-shark-immunoglobulin-light-chain/8248152