Abstract
By affinity chromatography with a monoclonal antibody (163B6), obtained in our laboratory, we have isolated a T. cruzi antigen which could be useful for differential diagnosis of Chagas' disease from leishmaniasis. This antigen, a 52-kD protein, reacted with all sera from Chagas' disease patients tested but not with sera from patients with leishmania, in ELISA. The 52-kD antigen is widely distributed in the Trypanosoma genus since the 163B6 monoclonal antibody reacts with T. rangeli and 8 strains and a clone of T. cruzi epimastigotes.
References
Aug 7, 1975·Nature·G Köhler, C Milstein
Jan 1, 1986·Zeitschrift Für Parasitenkunde·H TachibanaY Kaneda
May 12, 1989·Journal of Immunological Methods·D I Stott
Jan 1, 1986·The American Journal of Tropical Medicine and Hygiene·J L LemesreD Le Ray
Jun 1, 1986·Experimental Parasitology·L A MullerS M González Cappa
Jul 1, 1986·Infection and Immunity·F G Araujo
Jan 1, 1986·Transactions of the Royal Society of Tropical Medicine and Hygiene·R C WongP J Hindmarsh
Jan 1, 1987·Transactions of the Royal Society of Tropical Medicine and Hygiene·S Giovanni-De-SimoneB Galvao-Castro
Jul 1, 1985·The American Journal of Tropical Medicine and Hygiene·D Chao, D G Dusanic
Sep 1, 1985·Molecular and Biochemical Parasitology·E A DragonJ Manning
Nov 1, 1985·The American Journal of Tropical Medicine and Hygiene·J ScharfsteinL Mendonça-Previato
Nov 1, 1973·The American Journal of Tropical Medicine and Hygiene·B C WaltonO Eguia y Eguia
Oct 1, 1974·The Journal of protozoology·E L SeguraJ A Cerisola
Mar 27, 1981·Science·C R MerrilM H Ebert
Jul 1, 1984·The American Journal of Tropical Medicine and Hygiene·O OrozcoA Capron
Jan 1, 1983·Transactions of the Royal Society of Tropical Medicine and Hygiene·P DesjeuxS Mollinedo
Oct 1, 1981·Molecular and Biochemical Parasitology·D SnaryA K Allen
Jul 1, 1982·Infection and Immunity·F G AraujoJ S Remington
Citations
Jan 1, 1993·Vox Sanguinis·S Wendel, A L Gonzaga
Sep 1, 1994·Clinical and Experimental Immunology·E L MalchiodiR A Margni
Aug 17, 2004·Transactions of the Royal Society of Tropical Medicine and Hygiene·N J TarantoE L Malchiodi
Mar 20, 2003·FEMS Microbiology Letters·Iván S MarciparAriel M Silber
Jan 7, 2020·Biochimica Et Biophysica Acta. Molecular Basis of Disease·Augusto E BivonaEmilio L Malchiodi
Jun 1, 1994·Infection and Immunity·N W ZwirnerC A Fossati
Jan 1, 1993·Immunology Letters·E L MalchiodiJ J Cazzulo
Nov 8, 2003·Vaccine·Fernanda M FrankEmilio L Malchiodi
Sep 1, 2021·Journal of Medicinal Chemistry·Elany Barbosa da SilvaRafaela S Ferreira