PMID: 9545580Apr 18, 1998Paper

Isolation of cDNA encoding a novel human CC chemokine NCC-4/LEC

Biochimica Et Biophysica Acta
K ShoudaiH Nomiyama

Abstract

We have determined the entire sequence of human cDNA encoding a novel CC chemokine NCC-4 by 5' and 3' RACE methods. Two types of transcripts, 579 bp and 1503 bp long, respectively, are generated through alternative polyadenylation sites. Both species contain an open reading frame encoding 120 amino acids with 19-38% identity to other human CC chemokines. The short and long transcripts are expressed highly selectively in the liver at nearly equivalent levels. There seems to be one copy of the gene per haploid genome. We now designate NCC-4 as LEC from liver-expressed chemokine.

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Citations

Jun 14, 2002·Alcohol·Geoffrey HaydonDavid H Adams
Apr 23, 2002·Journal of Gastroenterology and Hepatology·Sarah Goddard, David H Adams
Mar 1, 2000·Molecular Pathology : MP·P F Lalor, D H Adams
Sep 29, 2011·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·A Y Del Valle-PineroW A Henderson
Apr 23, 1999·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·H NomiyamaO Yoshie
May 11, 1999·DNA and Cell Biology·S FukudaH Nomiyama
Mar 23, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Cristiana GuiducciMario P Colombo
Jul 22, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Takashi NakayamaOsamu Yoshie
Mar 8, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·M GiovarelliP Musiani
May 13, 2005·International Journal of Immunopathology and Pharmacology·T MussoM Giovarelli

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