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Isolation of lung tumor specific peptides from a random peptide library: generation of diagnostic and cell-targeting reagents

Cancer Letters

Dec 4, 2003

Tsuksa OyamaKathlynn C Brown

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Abstract

Discovery of ligands specific to receptor(s) on a surface of a cancer cell could impact clinical issues including functional diagnosis and cell-specific drug delivery. Using a phage display approach, we have isolated 20-mer peptide ligands that bind to 3 different human lung tumor cell ...read more

Mentioned in this Paper

Phage Display
Bacteriophages
Tumor Markers
Tumor Cells, Malignant
Lung Diseases
Target Cell Count
Polypeptides
Cell Type
Statistical Sensitivity
Ligands
28
Paper Details
References
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  • Citations57
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Isolation of lung tumor specific peptides from a random peptide library: generation of diagnostic and cell-targeting reagents

Cancer Letters

Dec 4, 2003

Tsuksa OyamaKathlynn C Brown

PMID: 14643452

DOI: 10.1016/j.canlet.2003.08.011

Abstract

Discovery of ligands specific to receptor(s) on a surface of a cancer cell could impact clinical issues including functional diagnosis and cell-specific drug delivery. Using a phage display approach, we have isolated 20-mer peptide ligands that bind to 3 different human lung tumor cell ...read more

Mentioned in this Paper

Phage Display
Bacteriophages
Tumor Markers
Tumor Cells, Malignant
Lung Diseases
Target Cell Count
Polypeptides
Cell Type
Statistical Sensitivity
Ligands
28

Feeds With Similar Papers

Bacteriophage: Phage Therapy

Phage therapy uses bacterial viruses (bacteriophages) to treat bacterial infections and is widely being recognized as an alternative to antibiotics. Here is the latest research.

Related Papers

Biosensors & Bioelectronics

Isolation of multiple cell-binding ligands from different phage displayed-peptide libraries

Biosensors & BioelectronicsJanuary 3, 2006
Tsukasa OyamaKathlynn C Brown
Journal of Molecular Biology

In vitro selection of a peptide with high selectivity for cardiomyocytes in vivo

Journal of Molecular BiologyAugust 18, 2004
Michael J McGuireKathlynn C Brown
Paper Details
References
  • References36
  • Citations57
1234
  • References36
  • Citations57
12345...

Download from

Publisher
PubMed
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