PMID: 2503663Jan 1, 1989Paper

Isolation of macrophage-activating phospholipid from Listeria monocytogenes

Medycyna doświadczalna i mikrobiologia
P JakoniukJ Borowski

Abstract

The aim of this study was isolate a factor, contained in phospholipid fraction of Listeria monocytogenes, responsible for macrophage activation. Lipids extracted from L. monocytogenes cells were subjected consecutively to fractionation on colons with silicic acid, Florisil and Sephadex LH-20. Separated fractions were assayed for their ability to activate macrophages as well as for their homogeneity by thin layer chromatography. Multistep fractionation procedure allowed to obtain the pure preparation of glycerophospholipid with a high ability for macrophage activation and capable to increase significantly anti-infections immunity in mice.

Related Concepts

Related Feeds

Candidiasis

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candidiasis (ASM)

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.