PMID: 6168660Sep 1, 1981Paper

Isolation of Mallory bodies and an attempt to demonstrate cell mediated immunity to Mallory body isolate in patients with alcoholic liver disease

Journal of Clinical Pathology
C GluudJ Nielsen

Abstract

Mallory bodies were isolated from necropsy livers from patients with alcoholic hepatitis with and without cirrhosis with a Ficoll viscosity barrier. The purity of Mallory bodies in the isolate varied between 70 and 90%, estimated by counting Mallory bodies and non-Mallory body structures in haematoxylin-eosin stained smears. Electron microscopy confirmed the presence of Mallory bodies in the isolates. The Mallory body isolate was used as antigen in the agarose leucocyte migration inhibition test in order to test the cell-mediated immunity. No significant difference in leucocyte migration was found between controls and patients with alcoholic hepatitis, alcoholic steatosis, alcoholic cirrhosis and miscellaneous liver diseases.

References

Apr 25, 1975·Annals of the New York Academy of Sciences·C M LeeveR Zetterman
Jan 1, 1977·Scandinavian Journal of Gastroenterology·J AldershvileP Skinhöj
Jan 1, 1974·Preparative Biochemistry·K OkamuraH Yokoo
Jan 1, 1981·Journal of Clinical Pathology·S M TriggsR N MacSween

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Citations

Jan 1, 1993·Journal of Gastroenterology and Hepatology·Y SakaiC Sato
Oct 1, 1986·Alcoholism, Clinical and Experimental Research·R D Johnson, R Williams
Feb 3, 2016·The American Journal of Pathology·Richard J W WilkinPhilip N Newsome
Jun 1, 1994·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·N Sheron
Nov 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K Jensen, C Gluud

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