PMID: 3099443Nov 1, 1986

Isolation of the proteolytic complex from industrial waste waters from streptomycin production

Ukrainskiĭ biokhimicheskiĭ zhurnal
I F MishuninS I Trofimova

Abstract

Dynamics of industrial biosynthesis of polyenzymic Streptomyces griseus system proteases and changes in their activities are studied in the process of streptomycin production. The method to isolate protease preparations is developed with optimization of production cycles of the stabilization, vacuum-concentration, ballast protein salting-out and lyophilization stages. The preparation is low toxic, retains 98% of the proteolytic activity at the temperature of 60 degrees C, 30 and 80%--under the effect of EDTA and urea, the activity maximum is at pH 7.0-8.0. The production technique of the preparation is estimated for its economic efficiency.

Related Concepts

Industrial Microbiology
Industrial Waste
Multienzyme Complexes
Peptide Hydrolases
Streptomyces griseus

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