PMID: 1179910Jan 1, 1975Paper

Isolation, purification and chemical composition of insoluble collagen from Guerin epithelioma.

Acta biochimica Polonica
E BańkowskiW Rzeczycki

Abstract

1. The insoluble collagen from Guerin epithelioma was isolated and its chemical composition was determined. The unusually high histidine content is accompanied in tumour collagen by a relatively small amount of lysine and arginine. 2. The isolated protein was strongly bound to glycoprotein, which could not be removed by EDTA treatment unless this procedure was preceded by digestion of the complex with trypsin.

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