Isoniazid induced childhood diabetes: A rare phenomenon

Journal of Basic and Clinical Pharmacy
Gutch ManishGupta Abhinav

Abstract

Drugs raise blood glucose concentrations via two broad mechanisms: By reducing insulin biosynthesis or secretion, or by reducing tissue sensitivity to insulin. Until date, there have been very few reported cases of isoniazid induced diabetes. We are presenting a case report of 6-year-old child with isoniazid induced diabetes who was misdiagnosed initially as a case of type 1 diabetes mellitus. We hereby stress that before diagnosing a patient with diabetes-type 1 or 2, a detailed history of drug intake for any such drugs, which can cause hyperglycemia has to be taken. Clear cut knowledge/cognizance of all such culprit drugs is therefore required.

References

Apr 1, 1993·Annals of Internal Medicine·M K PanditA N Peiris
Feb 7, 1953·British Medical Journal·G R LUNTZ, S G SMITH
Jan 18, 2013·Indian Journal of Nephrology·A SridharV Sivakumar

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Citations

Sep 16, 2015·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Neila FathallahChaker Ben Salem
Jun 3, 2018·Archives of Pharmacal Research·Mou-Ze LiuWei Zhang

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