Isotretinoin-induced Angle Closure and Myopic Shift

Journal of Glaucoma
Young-Myoung Park, Tae-Eun Lee

Abstract

To report and describe the management a rare case of transient bilateral angle closure with increased intraocular pressure (IOP) and myopic shift while on isotretinoin therapy for acne. A 28-year-old woman presented with bilateral myopic shift, angle closure with IOP increase, and supraciliary effusion 1 week after acne therapy with isotretinoin. Two weeks after stopping isotretinoin, and treatment with topical prednisolone acetate, atropine, and fixed combination of timolol and dorzolamide, refraction, IOP returned to normal and supraciliary effusions was decreased on ultrasound biomicroscopy. Oral isotretinoin for acne treatment may be associated with an adverse reaction, resulting in bilateral transient myopia and angle closure with IOP elevation.

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Citations

Jul 24, 2018·Cutaneous and Ocular Toxicology·Cahit Yavuz, Muammer Ozcimen
Jan 1, 2019·Ceská a slovenská oftalmologie : casopis Ceské oftalmologické spolecnosti a Slovenské oftalmologické spolecnosti·L HlavatáP Lišková
Jan 1, 2019·Ceská a slovenská oftalmologie : casopis Ceské oftalmologické spolecnosti a Slovenské oftalmologické spolecnosti·J ŠtěpánkováD Dotřelová
Apr 24, 2021·American Journal of Ophthalmology Case Reports·Aim-On SaengsirinavinNoppacharn Uaprasert
Oct 16, 2020·Cutaneous and Ocular Toxicology·Erdogan YasarEray Atalay

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