Italian Bipolar II vs I patients have better individual functioning, in spite of overall similar illness severity

CNS Spectrums
Bernardo Dell'OssoA Carlo Altamura

Abstract

Introduction Bipolar disorders (BDs) comprise different variants of chronic, comorbid, and disabling conditions, with relevant suicide and suicide attempt rates. The hypothesis that BD types I (BDI) and II (BDII) represent more and less severe forms of illness, respectively, has been increasingly questioned over recent years, justifying additional investigation to better characterize related sociodemographic and clinical profiles. A sample of 217 outpatients with Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR)-described BD (141 BDI, 76 BDII), without a current syndromal mood episode, was recruited, and sociodemographic and clinical characteristics of BDI and II patients were compared. BDII patients had significantly more favorable sociodemographics, in relation to occupational stability, cohabitation, and marital status. However, BDII compared with BDI patients had significantly longer duration of untreated illness, more frequent lifetime anxiety disorders comorbidity, longer most recent episode duration, higher rate of depressive first/most recent episode, and more current antidepressant use. In contrast, BDI compared with BDII patients had significantly more severe illness in t...Continue Reading

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Citations

Dec 10, 2016·Journal of Affective Disorders·Laura CremaschiA Carlo Altamura
Jan 20, 2019·The Australian and New Zealand Journal of Psychiatry·Alfredo Carlo AltamuraUNKNOWN ISBD Italian Chapter Epidemiological Group
Sep 5, 2017·Clinical Practice and Epidemiology in Mental Health : CP & EMH·M Carlotta PalazzoA Carlo Altamura
Nov 15, 2019·Bipolar Disorders·Alina KarantiMikael Landén
May 10, 2017·International Journal of Bipolar Disorders·Mirko ManchiaUmberto Albert
Apr 4, 2017·European Archives of Psychiatry and Clinical Neuroscience·A Carlo AltamuraEmilio Sacchetti
May 4, 2017·Journal of Psychopharmacology·Massimiliano BuoliA Carlo Altamura
Dec 17, 2019·International Journal of Bipolar Disorders·Francis BennettAditya N Sharma
Jan 27, 2017·International Journal of Bipolar Disorders·Bernardo Dell'OssoTerence A Ketter
Oct 27, 2020·The Journal of Nervous and Mental Disease·María Julieta LomastroDiego J Martino
Jul 13, 2020·Psychiatry Research·Gianluca SerafiniMario Amore
Oct 16, 2020·Early Intervention in Psychiatry·Massimiliano BuoliUNKNOWN ISBD Italian Chapter Epidemiologic Group

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