Iterative reconstruction: comparison of techniques for reduced-dose liver computed tomography following transarterial chemoembolization for hepatocellular carcinoma

Acta Radiologica
Min Jae ChaWon Jae Lee

Abstract

Background Adaptive statistical iterative reconstruction (ASIR) and model-based iterative reconstruction (MBIR) algorithms have the potential to reduce dose while maintaining image quality. Purpose To compare computed tomography (CT) image quality and diagnostic performance among three reconstruction techniques - ASIR, MBIR, and filtered back projection (FBP) - after transcatheter arterial chemoembolization (TACE) of hepatocellular carcinomas (HCC). Material and Methods Of 60 patients that underwent initial TACE for HCCs, half underwent dynamic liver CT with conventional scanning protocol, and the other half with dose reduction to approximately 60% of conventional exposure. All images were reconstructed using three algorithms: FBP, ASIR, and MBIR. For objective analysis, image noise and signal-to-noise ratio (SNR) were compared. For subjective analysis, three radiologists independently assessed image quality. Ability to detect viable HCCs was also evaluated. Results MBIR and ASIR produced images with less noise and higher SNR compared with FBP regardless of radiation dosage ( P < 0.017). However, in terms of subjective parameters, such as image blotchiness, artifacts, and overall quality, MBIR was inferior to FBP and ASIR ( P <...Continue Reading

References

Oct 31, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Hashem B El-Serag
Jan 31, 2012·Journal of Vascular and Interventional Radiology : JVIR·Daniel B BrownUNKNOWN Society of Interventional Radiology Standards of Practice Committee
Dec 15, 2012·European Journal of Radiology·Jeong-Ah LeeChoong Ki Park
Jun 26, 2013·AJR. American Journal of Roentgenology·Amy K HaraDushyant V Sahani
Oct 12, 2013·AJNR. American Journal of Neuroradiology·J M HoxworthA K Hara
Jul 24, 2015·AJR. American Journal of Roentgenology·Sana BoudabbousXavier Montet

❮ Previous
Next ❯

Methods Mentioned

BETA
imaging technique

Software Mentioned

SPSS
MedCalc
PASW

Related Concepts

Related Feeds

Carcinoma, Hepatocellular

Hepatocellular Carcinoma is a malignant cancer in liver epithelial cells. Discover the latest research on Hepatocellular Carcinoma here.