It's the network, stupid: a population's sexual network connectivity determines its STI prevalence

F1000Research
Chris R Kenyon, Wim Delva

Abstract

There is little consensus as to why sexually transmitted infections (STIs), including HIV and bacterial vaginosis (BV) are more prevalent in some populations than others. Using a broad definition of sexual network connectivity that includes both structural and conductivity-related factors, we argue that the available evidence suggests that high prevalence of traditional STIs, HIV and BV can be parsimoniously explained by these populations having more connected sexual networks. Positive feedback, whereby BV and various STIs enhance the spread of other STIs, then further accentuates the spread of BV, HIV and other STIs. We review evidence that support this hypothesis and end by suggesting study designs that could further evaluate the hypothesis, as well as implications of this hypothesis for the prevention and management of STIs.

References

Feb 1, 1992·Mathematical Biosciences·C H Watts, R M May
Nov 3, 1990·BMJ : British Medical Journal·G Rose, S Day
Jan 1, 1997·Sexually Transmitted Diseases·A C GhaniG P Garnett
Apr 1, 1997·AIDS·M Morris, M Kretzschmar
Oct 27, 1997·The New England Journal of Medicine·D T FlemingM E St Louis
Apr 1, 1978·Sexually Transmitted Diseases·J A YorkeA Nold
Jun 12, 1999·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·G P GarnettM E St Louis
Dec 22, 1999·American Journal of Epidemiology·J J PotteratH A White
Jun 16, 2001·AIDS·E LagardeUNKNOWN Study Group on Heterogeneity of HIV Epidemics in African Cities
Sep 21, 2001·Journal of Urban Health : Bulletin of the New York Academy of Medicine·A M JollyJ J Potterat
Nov 1, 2001·AIDS·A BuvéUNKNOWN Study Group on Heterogeneity of HIV Epidemics in African Cities
Apr 20, 2002·Epidemiology·Adaora A AdimoraTonya R Stancil
Aug 13, 2002·Sexually Transmitted Diseases·Pamina M GorbachKing K Holmes
Jul 29, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Thomas L CherpesSharon L Hillier
Aug 15, 2003·Sexually Transmitted Diseases·Harrell W ChessonSevgi O Aral
Apr 21, 2004·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Paul K DrainKing K Holmes
May 1, 2004·Science·Rand L Stoneburner, Daniel Low-Beer
Jul 14, 2004·JAMA : the Journal of the American Medical Association·Nicole CrepazGary Marks
Jun 21, 2005·Infectious Disease Clinics of North America·Kevin A Fenton, John Imrie
Feb 4, 2006·Science·Simon GregsonRoy M Anderson
Apr 4, 2006·Sexually Transmitted Infections·B ChelugetJ Stover
May 3, 2006·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Adaora A AdimoraRobert E Fullilove
Jul 20, 2006·Journal of the Royal Society, Interface·Matt J Keeling, Ken T D Eames
Aug 24, 2006·JAMA : the Journal of the American Medical Association·Fujie XuLauri E Markowitz
Feb 28, 2007·Sexually Transmitted Diseases·Kevin A Fenton, Judith N Wasserheit
Aug 1, 2007·Sexually Transmitted Infections·Sevgi O AralKing K Holmes
Aug 30, 2007·Sexually Transmitted Infections·Sevgi O AralJames Blanchard
Oct 25, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Katherine A FethersCatriona S Bradshaw
Apr 18, 2009·American Journal of Public Health·Martina MorrisSteve Wakefield
May 16, 2009·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Gabriela Paz-BaileyEdgar Monterroso
Oct 30, 2009·The Journal of Infectious Diseases·Katherine A FethersCatriona S Bradshaw

❮ Previous
Next ❯

Citations

Jun 30, 2019·Frontiers in Public Health·Chris Kenyon
Jul 19, 2021·The Lancet Child & Adolescent Health·Jami S LeichliterOluyomi A Obafemi
Jan 5, 2022·International Journal of STD & AIDS·Chris KenyonChristophe Van Dijck

❮ Previous
Next ❯

Methods Mentioned

BETA
circumcision
contraception

Software Mentioned

MeasureDHS

Related Concepts

Related Feeds

Bacterial Vaginosis

Bacterial vaginosis can increase the risk of sexually transmitted infections and in rare cases lead to pelvic inflammatory diseases. Discover the latest research on Bacterial Vaginosis here.