Ivabradine for systolic heart failure

JAAPA : Official Journal of the American Academy of Physician Assistants
Courtney M Meade, Jennifer N Clements

Abstract

Ivabradine works in the sinoatrial node to prolong diastolic depolarization and reduce heart rate. In patients with chronic systolic heart failure, this drug has reduced the risk of hospitalization when used in combination with other optimal pharmacotherapy.

References

Dec 18, 2013·The American Journal of Cardiology·Jeffrey S BorerUNKNOWN SHIFT Investigators
Jan 1, 2014·Expert Opinion on Drug Metabolism & Toxicology·Gian Marco RosaClaudio Brunelli
Jun 26, 2014·European Journal of Heart Failure·Michel KomajdaUNKNOWN SHIFT Investigators
Sep 2, 2014·The New England Journal of Medicine·Kim FoxUNKNOWN SIGNIFY Investigators

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