PMID: 2492357Jan 1, 1989Paper

IVF: induction of ovulation in poor responders

Journal of Steroid Biochemistry
P G CrosignaniH Wyssling

Abstract

All IVF programs have a consistent rate of failure in inducing ovulations. Pharmacological induction of ovulation is otherwise crucial for an IVF program because of the need for more than one ovum. Since it is well known that the best candidates for HMG treatment are hypogonadotropic women a short reversible hypogonadotropic state was induced in IVF patients by LH-RH agonist (Buserelin). Superovulation was then achieved with very high initial doses of FSH (Metrodin) in order to maximize the ovarian response. This technique used in 116 IVF women induced a satisfactory follicle growth even in 70% of the patients already poorly responsive to HMG stimulation.

References

Mar 1, 1986·Clinical Obstetrics and Gynecology·G D Hodgen
Oct 1, 1987·Journal of in Vitro Fertilization and Embryo Transfer : IVF·J L Yovich
May 1, 1984·The Australian & New Zealand Journal of Obstetrics & Gynaecology·J F KerinL W Cox

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Citations

Apr 23, 2005·Journal of Assisted Reproduction and Genetics·Shai E ElizurJehoshua Dor
Nov 24, 2007·Journal of Assisted Reproduction and Genetics·D LoutradisA Antsaklis
Jun 19, 2002·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Y KhalafP Braude
Sep 20, 2005·Reproductive Biomedicine Online·Roberto MarciMassimo Moscarini
May 29, 2002·Current Opinion in Obstetrics & Gynecology·Neal G Mahutte, Aydin Arici
Feb 4, 2006·Clinical Obstetrics and Gynecology·William B Schoolcraft
Mar 2, 2005·Obstetrics and Gynecology·Akira IwaseShigehiko Mizutani
Nov 23, 2006·Fertility and Sterility·Neal G Mahutte, Aydin Arici
Dec 3, 2003·Annals of the New York Academy of Sciences·Dimitris LoutradisStylianos Michalas
Jul 27, 2007·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·C S Siristatidis, M P Hamilton
Feb 14, 1998·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·H P Van de Water
Jun 2, 2018·Minerva ginecologica·Paolo G ArtiniVito Cela
Jun 27, 2020·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Carlo BullettiAlberto Vaiarelli
Oct 2, 2012·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Yannis PrapasNikos Prapas

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