IVF pregnancies: neonatal outcomes after the new Italian law on assisted reproduction technology (law 40/2004)

Acta Obstetricia Et Gynecologica Scandinavica
Donatella CasertaMassimo Moscarini

Abstract

To compare maternal and neonatal outcome of pregnancies achieved by assisted reproduction technique (ART) according to the guidelines of the newly established Italian ART law 40/2004, with that of naturally conceived. Three hundred and sixty-four ART pregnancies and 304 naturally conceived pregnancies were analyzed in terms of the incidence of obstetric complications and perinatal outcome. Control group was enrolled prospectively after being matched for an extensive number of maternal characteristics. Among singletons, ART pregnancies when compared to naturally conceived pregnancies showed a higher incidence of pregnancy loss (23.4% versus 10.5%) and a lower mean birth weight. A higher but not significant incidence of small for gestational age fetuses was observed in ART pregnancies, compared to those from normally conceived pregnancies (7.2% versus 2.7%). Moreover, the ART pregnancies showed a slightly, but nonetheless significantly shorter mean gestational age (38.6 versus 39.3 weeks) and more frequent preterm deliveries (11%) than the control group (2.7%). No difference was found in terms of other obstetric complications such as pregnancy-induced hypertension, gestational diabetes and placental abruption. Neonatal outcome wa...Continue Reading

Citations

Apr 13, 2012·Journal of Human Hypertension·C ThomopoulosC Stefanadis
Mar 2, 2013·Human Reproduction Update·Michèle HansenCarol Bower
Jul 1, 2010·Annals of African Medicine·Haifa A Al-Turki
Mar 15, 2014·Journal of Immigrant and Minority Health·Donatella CasertaFlaviano Moscarini
Oct 28, 2009·Current Opinion in Endocrinology, Diabetes, and Obesity

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