Japan Arteriosclerosis Longitudinal Study-Existing Cohorts Combine (JALS-ECC): rationale, design, and population characteristics

Circulation Journal : Official Journal of the Japanese Circulation Society
Japan Arteriosclerosis Longitudinal Study (JALS) Group

Abstract

The Japan Arteriosclerosis Longitudinal Study-Existing Cohorts Combine (JALS-ECC) is a pooled study based on individual participant data from existing prospective cohort studies in Japan. Its purpose was to consider associations between risk factors and cardiovascular disease (CVD) outcomes, as well as differences between subgroups, defined by age, gender or geographical region, which could not be detected in the smaller samples. Individual records for 66,691 participants in 21 cohort studies were pooled, accounting for a total of 575,628 person-years. From this data, there were 409 deaths attributed to stroke and 169 deaths attributed to coronary heart disease (CHD). Total stroke and CHD events were 1,478 and 178, respectively. Of the 1,424 total stroke events with a reported stroke subtype, 975 were classified as ischemic, 267 as hemorrhagic, and 178 as subarachnoid hemorrhage. The JALS-ECC collected data from existing cohort studies covering a diverse Japanese population, which has provided information about the effects of modifiable factors on the risks of the CVD. Such information should provide a reliable basis for establishing prevention strategies.

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Citations

Jun 8, 2010·Circulation Journal : Official Journal of the Japanese Circulation Society·Naohito TanabeUNKNOWN Japan Arteriosclerosis Longitudinal Study Group
May 21, 2014·Journal of Diabetes Investigation·Masayuki KatoMitsuhiko Noda
Nov 16, 2011·Biostatistics·Masataka TaguriHirotsugu Ueshima
Apr 28, 2017·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Kei Asayama
May 10, 2017·Journal of Hypertension·Kei AsayamaUNKNOWN Japan Arteriosclerosis Longitudinal Study (JALS) group
Apr 1, 2009·Circulation·Katsuyuki MiuraUNKNOWN Japan Arteriosclerosis Longitudinal Study (JALS) Group
Aug 12, 2010·Circulation. Cardiovascular Quality and Outcomes·Hiroshi YatsuyaUNKNOWN Japan Arteriosclerosis Longitudinal Study (JALS) group
Apr 11, 2009·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Yoshitaka Fujii, Michiyo Itakura
Mar 17, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Toshihiko DoiAtsushi Ohtsu
Jul 5, 2011·Intellectual and Developmental Disabilities·William E KiernanDavid M Mank
Apr 10, 2009·PharmacoEconomics·Ataru IgarashiKiichiro Tsutani
Jun 13, 2009·Circulation Journal : Official Journal of the Japanese Circulation Society·Yu SunYuan-Teh Lee

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