Java project on periodontal diseases: serotype distribution of Aggregatibacter actinomycetemcomitans and serotype dynamics over an 8-year period

Journal of Clinical Periodontology
Wil A van der ReijdenA J van Winkelhoff

Abstract

To investigate the serotype distribution and stability of Aggregatibacter actinomycetemcomitans over an 8-year period in untreated Indonesian subjects. Clinical periodontal status and the presence of A. actinomycetemcomitans were established in 1994 and 2002 in 107 subjects from an Indonesian tea estate deprived from dental care. On an average, 3.6 isolates per patient were subcultured and serotyped using specific PCR reactions. In 1994, the predominant serotype was b (53.7%), whereas a and c occurred in 17.1% and 14.6% of the subjects, respectively. In 2002, a reduction in serotypes a (7.5%) and b (30.2%) occurred. Serotypes c and e increased in prevalence from 14.6% to 35.8% and 2.4% to 9.4%, respectively. Multiple serotypes were found in 12.2% in 1994 and 17% in 2002. From 24 subjects who were positive at both time points, 14 (58.3%) had the same serotype, whereas in 10 subjects (41.7%), a different serotype was found. Mean clinical attachment loss had increased from 0.74 mm in 1994 to 1.96 mm in 2002 but could not be related to subgingival presence of A. actinomycetemcomitans. A. actinomycetemcomitans serotypes distribution in Indonesian young adults shifts from predominantly serotype b to a more equal prevalence of serotyp...Continue Reading

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Citations

Jul 27, 2010·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Wil A van der ReijdenPaul de Vos
Apr 20, 2011·Periodontology 2000·Esmonde F Corbet, W Keung Leung
Apr 5, 2012·Journal of Clinical Periodontology·Panwadee BandhayaKitti Torrungruang
Apr 18, 2014·Periodontology 2000·Eija Könönen, Hans-Peter Müller
Feb 23, 2010·Archives of Oral Biology·Caio Vinicius Gonçalves Roman-TorresJosé Roberto Cortelli
Oct 18, 2015·Archives of Oral Biology·Nuntiya PahumuntoRawee Teanpaisan
Sep 22, 2009·Journal of Dental Research·D HaubekK Poulsen
Jul 3, 2017·Journal of Global Antimicrobial Resistance·Chaido AkrivopoulouDerren Ready

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