PMID: 2502485Jun 1, 1989Paper

Jejunal motility during cyclic total parenteral nutrition in patients with Crohn's disease

Gut
P DucrotteR Colin

Abstract

Our aim was to study the jejunal motility (a) in seven patients receiving longterm (median: 24 days) cyclic total parenteral nutrition (CTPN) for an acute exacerbation of Crohn's disease involving the ileum and/or the colon without any sign of occlusion and (b) in six healthy volunteers undergoing the same parenteral nutrition for one day after an overnight fast. Continuous recordings, lasting 20 hours, were carried out in patients after correction of their nutritional status and significant improvement of the Crohn's disease activity index. In five of the seven patients, we recorded seven to 14 phase III episodes (PIII) (median: 10), both more frequent and slower during the nocturnal part of the recording time as compared with diurnal. Seven to 18 PIIIs (median: 12) were found in controls. The overall duration of the motor activity was not different between these five patients and controls. In the remaining two patients, no PIII episode was recorded and 79% and 57% respectively of the whole recording time consisted of irregular motor activity. Our work therefore, shows that: (a) PIIIs remain and have a circadian variation in their periodicity and propagation velocity, in most of our patients undergoing longterm CTPN (b) CTPN d...Continue Reading

References

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Citations

Jun 1, 1995·Journal of the American College of Nutrition·E R Briones, F L Iber
Jan 15, 2014·World Journal of Gastroenterology : WJG·Gabrio BassottiVito Annese
Apr 12, 2005·The Journal of Surgical Research·Mikael EkelundEva Ekblad
Mar 1, 1996·JPEN. Journal of Parenteral and Enteral Nutrition·G RiachiE Lerebours
Dec 12, 2018·Inflammatory Bowel Diseases·Gengqing SongJean-Paul Achkar
Dec 17, 1997·Scandinavian Journal of Gastroenterology·V AnneseG Vantrappen
Oct 26, 1991·BMJ : British Medical Journal·N D Maynard, D J Bihari
Feb 18, 2020·Techniques in Coloproctology·G BassottiG Maconi

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