Job strain and risk of esophageal and cardia cancers

Cancer Epidemiology
Catarina JanssonJ Lagergren

Abstract

Few studies have investigated work-related stress in relation to esophageal or cardia cancers. Our nationwide Swedish population-based case-control study included 189 and 262 esophageal and cardia adenocarcinoma cases respectively, 167 esophageal squamous-cell carcinoma cases and 820 controls. We derived each study participant's occupation of longest duration from occupational histories and applied a psychosocial job-exposure matrix. Odds ratios (ORs) with 95% confidence intervals (CIs) were estimated using conditional logistic regression, in multivariable models. Job strain was positively associated with risk of esophageal adenocarcinoma (OR 3.2, 95% CI 1.0-9.8) and squamous-cell carcinoma (OR 4.0, 95% CI 1.6-10.5), but not with cardia adenocarcinoma. No associations regarding demands, control, social support or iso strain were observed, except for a positive association between high control and risk of esophageal squamous-cell carcinoma (OR 1.5, 95% CI 1.0-2.3). Job strain seems to increase the risk of both histological types of esophageal cancer.

References

Feb 1, 1993·Scandinavian Journal of Work, Environment & Health·J V Johnson, W F Stewart
Mar 18, 1999·The New England Journal of Medicine·J LagergrenO Nyrén
Aug 3, 2000·International Journal of Epidemiology·A A BotterweckP A van Den Brandt
Oct 18, 2000·International Journal of Epidemiology·A J van LoonJ Ormel
Dec 6, 2003·The New England Journal of Medicine·Peter C Enzinger, Robert J Mayer
Nov 25, 2004·American Journal of Epidemiology·Eva S SchernhammerIchiro Kawachi
Oct 29, 2005·International Archives of Occupational and Environmental Health·Mikko LaaksonenEero Lahelma
Jan 20, 2006·Occupational and Environmental Medicine·C JanssonJ Lagergren

❮ Previous
Next ❯

Citations

Feb 9, 2013·BMJ : British Medical Journal·Katriina HeikkiläUNKNOWN IPD-Work Consortium
Apr 5, 2013·World Journal of Gastroenterology : WJG·Paul DenverLesley A Anderson
Nov 29, 2017·Frontiers in Oncology·Audrey Blanc-LapierreMarie-Elise Parent
Nov 30, 2018·International Journal of Cancer. Journal International Du Cancer·Tingting YangYongchun Chen
Apr 27, 2011·Clinical Transplantation·Carol S StilleyMichael E deVera
Mar 18, 2017·Psychosomatic Medicine·Claudia Trudel-FitzgeraldShelley S Tworoger

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Incidence & Mortality

Cancer has emerged as a global concern due to its increase in incidence and mortality. Efforts are underway to evaluate and develop action plans to reduce the global burden of cancer. Currently, lung cancer, breast cancer and prostate cancer are the leading causes of cancer mortality. Here is the latest research on cancer incidence and mortality.

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.