Johanson-Blizzard syndrome--a case study, behavioral manifestations, and successful treatment strategies

Biological Psychiatry
John F Prater, Karyn D'Addio

Abstract

Mental retardation has multiple causes, including genetic, and is often accompanied by severe behavioral difficulties. These behavioral problems frequently disrupt care, reduce quality of life, and represent risk of injury. In treating special populations where biologic interventions are most important, the psychiatrist must often combine appropriate pharmacologic interventions with behavioral strategies, employing staff support and using a multidisciplined team approach. This article reviews a case in which a person with Johanson-Blizzard syndrome, a rare genetic disorder whose physical manifestations have been described in the literature, is successfully treated using a combination of psychotropic medication and behavioral programming. Target behaviors of severe obsessive compulsive disorder and aggression were ameliorated using these strategies.Currently, specific pharmacologic interventions in combination with structured behavioral programming represents the most successful method of dealing with various forms of behavioral problems linked to mental retardation.

References

Apr 1, 1990·American Journal of Medical Genetics·R Gershoni-BaruchA Benderly
Sep 1, 1985·American Journal of Medical Genetics·J B Moeschler, M S Lubinsky
Feb 1, 1996·Pediatric Clinics of North America·A LernerE Lebenthal
Jun 1, 1997·The Psychiatric Clinics of North America·M Fava
Sep 15, 2000·The Psychiatric Clinics of North America·N AttiullahS A Rasmussen
Sep 15, 2000·The Psychiatric Clinics of North America·E HollanderC Cartwright

❮ Previous
Next ❯

Citations

Mar 7, 2013·Birth Defects Research. Part A, Clinical and Molecular Teratology·Curtis K DeutschLewis B Holmes
Mar 24, 2007·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·William H HoffmanFarivar Yaghmai
Jun 18, 2010·European Journal of Pediatrics·Nima RezaeiMartin Zenker

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anxiety Disorders

Discover the latest research on anxiety disorders including agoraphobia, panic disorder, obsessive-compulsive disorder, and post-traumatic stress disorder here.

Related Papers

Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie
J N McheikG Levard
Paediatric Anaesthesia
Christopher R FichterJoseph D Tobias
Endocrinology and Metabolism Clinics of North America
Martin ZenkerMarkus M Lerch
Australian and New Zealand Journal of Medicine
S K SamantrayA Bhaktaviziam
© 2022 Meta ULC. All rights reserved