Joint hypermobility syndromes

Current Opinion in Rheumatology
M L Raff, P H Byers

Abstract

Inherited connective tissue disorders, among them Ehlers-Danlos syndrome, osteogenesis imperfecta, Marfan syndrome, and Larsen syndrome, are characterized by generalized joint hypermobility. Others, such as Morquio syndrome or achondroplasia, have hypermobility in a more limited distribution. Recent clinical and molecular genetic studies have defined the range of clinical variation and the underlying molecular defects in several disorders. These studies provide hope that more common varieties of joint hypermobility can be understood and that effective therapies are within reach.

Citations

Sep 2, 2011·Rheumatology International·Colin R Paterson, Patricia A Mole
May 3, 2001·Current Opinion in Rheumatology·I MaldonadoA J Reginato
Oct 14, 2006·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·B Berglund, G Nordström
Apr 19, 2015·Journal of Molecular and Cellular Cardiology·Loren E DupuisChristine B Kern
Jul 31, 2008·American Journal of Medical Genetics. Part a·Michael BoberCharles Scott
Mar 29, 2002·Infectious Disease Clinics of North America·Shireen V Guide, Steven M Holland
Jul 7, 2018·Expert Review of Clinical Pharmacology·Anwar Baban, Marco Castori
Jul 28, 2006·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Ana MonteagudoIlan E Timor-Tritsch
Jun 29, 2002·The Journal of Biological Chemistry·Karl J JepsenShukti Chakravarti

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