Joint lavage associated with triamcinolone hexacetonide injection in knee osteoarthritis: a randomized double-blind controlled study.

Clinical Rheumatology
Leandro ParmigianiJamil Natour

Abstract

Compare the medium-term effectiveness and tolerance between joint lavage (JL) in combination with triamcinolone hexacetonide (TH) intra-articular injection (IAI) and IAI with TH alone for treatment of primary osteoarthritis (OA) of the knee. A randomized, double-blind, controlled study was carried out on 60 patients with primary OA of the knee, randomized into two intervention groups: JL/TH group, joint lavage in combination with TH intra-articular injection and TH group, TH intra-articular injection. Patients were followed for 12 weeks by a blind observer using the following outcome measurements: visual analogue scale for pain at rest and in movement, goniometry, WOMAC, Lequesne's index, timed 50-ft walk, perception of improvement, Likert scale for improvement assessment, use of nonsteroidal anti-inflammatory drugs and analgesics, and local side effects. There were no statistical differences in the inter-group analysis for any of the variables studied over the 12-week period. Although both groups demonstrated statistical improvement in the intra-group evaluation (except for Likert scale according to patient and the use of anti-inflammatory drugs). In the Kellgren-Lawrence scale (KL) 2 and 3 sub-analysis, there was a statistica...Continue Reading

References

Nov 1, 1991·The Journal of Bone and Joint Surgery. British Volume·P J LivesleyA Moulton
Jan 1, 1987·Scandinavian Journal of Rheumatology. Supplement·M G LequesneP Gerard
Sep 25, 2001·Best Practice & Research. Clinical Rheumatology·M C Hochberg, M Dougados
Dec 1, 1957·Annals of the Rheumatic Diseases·J H KELLGREN, J S LAWRENCE

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Citations

Dec 7, 2014·Revista brasileira de reumatologia·Rita Nely Vilar FurtadoJamil Natour
Oct 23, 2015·The Cochrane Database of Systematic Reviews·Peter JüniBruno R da Costa
Jul 20, 2019·The Cochrane Database of Systematic Reviews·Jonathan S PalmerAndrew J Price
Jun 8, 2017·Orthopaedic Journal of Sports Medicine·Maximilian A MeyerBrian J Cole

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