Jörg Langowski: his scientific legacy and the future it promises

BMC Biophysics
Giuseppe ChiricoKatalin Tóth

Abstract

With the passing of Jörg Langowski 6 May 2017 in a sailplane accident, the scientific community was deprived of a strident and effective voice for DNA and chromatin molecular and computational biophysics, for open access publishing and for the creation of effective scientific research networks. Here, after reviewing some of Jörg's key research contributions and ideas, we offer through the personal remembrance of his closest collaborators, a deep analysis of the major results of his research and the future directions they have engendered. The legacy of Jörg Langowski has been to propel a way of viewing biological function that considers living systems as dynamic and in three dimensions. This physical view of biology that he pioneered is now, finally, becoming established also because of his great effort.

References

Feb 20, 1992·Journal of Molecular Biology·T Schlick, W K Olson
Mar 7, 1989·Biochemistry·T D YagerK E van Holde
Dec 15, 1986·Biophysical Chemistry·J LangowskiC Lehmann
Jun 1, 1985·Biopolymers·J LangowskiJ M Schurr
Jan 25, 1974·Science·A L Olins, D E Olins
Aug 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·D ShoreR L Baldwin
Nov 20, 1993·Journal of Molecular Biology·D J ClarkH Eisenberg
Aug 1, 1996·Biophysical Journal·G Chirico, J Langowski
Nov 14, 1998·Journal of Molecular Biology·H JianA Vologodskii
Aug 10, 2000·Biopolymers·K Klenin, J Langowski
Mar 22, 2003·Current Opinion in Cell Biology·Wolfgang FischleC David Allis
Feb 25, 2005·Proceedings of the National Academy of Sciences of the United States of America·Miroslav TomschikSanford H Leuba
Mar 18, 2005·The Journal of Biological Chemistry·Cyril ClaudetJan Bednar
Feb 8, 2006·Biochemistry·Katalin TóthJörg Langowski
Mar 21, 2006·The European Physical Journal. E, Soft Matter·J Langowski
Oct 16, 2007·Biophysical Journal·L KelbauskasD Lohr
Feb 14, 2008·Journal of Computational Chemistry·Karine VoltzJeremy Smith
Aug 1, 2009·Science·Courtney HodgesCarlos Bustamante
Aug 25, 2009·Nature Structural & Molecular Biology·Michael G PoirierJonathan Widom
Aug 27, 2009·Proceedings of the National Academy of Sciences of the United States of America·Alexander GansenClaus A M Seidel
Dec 24, 2010·Nucleic Acids Research·Vera BöhmJörg Langowski
Jul 20, 2011·Proceedings of the National Academy of Sciences of the United States of America·Marek SimonMichael G Poirier
Dec 31, 2011·PLoS Computational Biology·Mithun BiswasJörg Langowski
Mar 6, 2012·Biophysical Journal·Karine VoltzJörg Langowski
Sep 12, 2012·Nucleic Acids Research·Justin A NorthMichael G Poirier
May 3, 2013·PloS One·Alexander GansenJörg Langowski
Jul 12, 2013·Cytometry. Part a : the Journal of the International Society for Analytical Cytology·Katalin TóthJörg Langowski

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Methods Mentioned

BETA
light scattering
AFM
fluorescence microscopy
cross-correlation spectroscopy
FCS
FRET
Hi-C
Fluorescence
fluorescence correlation spectroscopy
ChIP-Seq

Software Mentioned

PloS
spFRET
One

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