Journey of the S‑ICD to first-line therapy

Herzschrittmachertherapie & Elektrophysiologie
Elif KayaTienush Rassaf

Abstract

The subcutaneous implantable cardioverter-defibrillator (S-ICD®, Boston Scientific, Marlborough, MA, USA, previously Cameron Health, San Clemente, CA, USA) represents an important milestone in ICD therapy for prevention of sudden cardiac death (SCD). Since the introduction of the S‑ICD in 2010, the device has undergone further development. Based on the unique feature of an entirely extracardiac implantation, the S‑ICD is able to reduce the common perioperative and long-term complications of the usual endovascular implanted ICD systems. Especially for patients with a complex anatomy and no option of an endovascular lead implantation, the S‑ICD offers a potential alternative. Regarding the initial uncertainty if this innovative ICD approach is actually reliable in detecting and terminating ventricular arrhythmias has been resolved by multiple clinical studies and trials providing evidence for an effective treatment. Based on the obvious advantages compared to conventional ICD systems, the question arises if the S‑ICD should actually be the first choice in the majority of all primary prevention patients in the future. Furthermore, recent data from large registries show that S‑ICD indications are also expanding in secondary prevent...Continue Reading

References

Mar 22, 2002·The New England Journal of Medicine·Arthur J MossUNKNOWN Multicenter Automatic Defibrillator Implantation Trial II Investigators
Jun 7, 2008·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Andrew E EpsteinUNKNOWN Society of Thoracic Surgeons
May 28, 2013·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Reinoud E KnopsArthur A M Wilde
Mar 29, 2014·European Heart Journal·Pier D LambiaseUNKNOWN EFFORTLESS Investigators
Feb 4, 2016·Revista Española De Cardiología·Silvia G PrioriDirk J Van Veldhuisen
Nov 5, 2016·Journal of the American College of Cardiology·Tom F BrouwerReinoud E Knops
Aug 12, 2017·Journal of the American College of Cardiology·Lucas BoersmaUNKNOWN EFFORTLESS Investigator Group

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