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Journey to the Center of the Mitochondria Guided by the Tail Anchor of Protein Tyrosine Phosphatase 1B

bioRxiv

Nov 22, 2013

Julia FuellerAli Kinkhabwala

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Abstract

The canonical protein tyrosine phosphatase PTP1B has traditionally been considered to exclusively reside on the endoplasmic reticulum (ER). Using confocal microscopy, we show that endogenous PTP1B actually exhibits a higher local concentration at the mitochondria in all mammalian cell l...read more

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Amino Acid [EPC]
Ophthalmomandibulomelic Dysplasia
Catalytic Domain
Energy Transfer
Protein Tyrosine Phosphatase
Mutant
Lipids
Study
Mammalian Cell
ASNA1 gene
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  • Journey to the Center of the Mitochondria Guided by the Tail Anchor of Protein Tyrosine Phosphatase 1B

    bioRxiv

    Nov 22, 2013

    Julia FuellerAli Kinkhabwala

    PMID: 990000836

    DOI: 10.1101/000836

    Abstract

    The canonical protein tyrosine phosphatase PTP1B has traditionally been considered to exclusively reside on the endoplasmic reticulum (ER). Using confocal microscopy, we show that endogenous PTP1B actually exhibits a higher local concentration at the mitochondria in all mammalian cell l...read more

    Mentioned in this Paper

    Amino Acid [EPC]
    Ophthalmomandibulomelic Dysplasia
    Catalytic Domain
    Energy Transfer
    Protein Tyrosine Phosphatase

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