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Journey to the Center of the Mitochondria Guided by the Tail Anchor of Protein Tyrosine Phosphatase 1B

bioRxiv

Nov 22, 2013

Julia FuellerAli Kinkhabwala

Abstract

The canonical protein tyrosine phosphatase PTP1B has traditionally been considered to exclusively reside on the endoplasmic reticulum (ER). Using confocal microscopy, we show that endogenous PTP1B actually exhibits a higher local concentration at the mitochondria in all mammalian cell l...read more

Mentioned in this Paper

Establishment and Maintenance of Localization
Health Center
Study
EGFR
Biochemical Pathway
ASNA1 gene
Energy Transfer
Carboxy-Terminal Amino Acid
Membrane
Mitochondrial Inheritance
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Journey to the Center of the Mitochondria Guided by the Tail Anchor of Protein Tyrosine Phosphatase 1B

bioRxiv

Nov 22, 2013

Julia FuellerAli Kinkhabwala

PMID: 990000836

DOI: 10.1101/000836

Abstract

The canonical protein tyrosine phosphatase PTP1B has traditionally been considered to exclusively reside on the endoplasmic reticulum (ER). Using confocal microscopy, we show that endogenous PTP1B actually exhibits a higher local concentration at the mitochondria in all mammalian cell l...read more

Mentioned in this Paper

Establishment and Maintenance of Localization
Health Center
Study
EGFR
Biochemical Pathway
ASNA1 gene
Energy Transfer
Carboxy-Terminal Amino Acid
Membrane
Mitochondrial Inheritance

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