PMID: 11907393Mar 22, 2002Paper

Jugular venous oxygen saturation thresholds in trauma patients may not extrapolate to ischemic stroke patients: lessons from a preliminary study

Journal of Neurosurgical Anesthesiology
Emanuela KellerW Hacke

Abstract

The authors' first examinations of 10 patients with severe hemispheric stroke indicate that bedside monitoring of cerebral blood flow (CBF) is of clinical value as a prognostic tool for outcome and as therapy of elevated intracranial pressure (ICP). Jugular venous oximetry, which is easier to handle and provides on-line data, may also be of prognostic value in patients with ischemic stroke. No clinical studies are available on patients with hemispheric infarctions. Therefore, in a second data analysis from the same patient population, the authors' objective was to estimate the clinical value of monitoring cerebral hemodynamics and metabolism with jugular bulb catheters in treatment of severe postischemic brain edema. In 10 patients with severe hemispheric infarctions, ICP, jugular venous oxygen saturation (SjvO2), CBF, and cerebral metabolic rate of oxygen (CMRO2) were measured prospectively. A total of 101 ICP, SjvO2, and 92 CBF measurements were obtained. Only two SjvO2 values were below the critical thresholds to detect secondary ischemic events defined in trauma patients (SjvO2 < 50%). Intracranial pressure elevations more than 20 mm Hg and pupillary disturbances were treated with osmotherapy (mannitol or hypertonic NaCl hy...Continue Reading

References

Feb 1, 1992·Journal of Neurosurgery·M SheinbergR G Grossman
Oct 1, 1989·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·M Jakobsen, E Enevoldsen
Nov 1, 1981·Stroke; a Journal of Cerebral Circulation·J AstrupL Symon
May 1, 1983·Stroke; a Journal of Cerebral Circulation·W D Heiss
Jul 1, 1995·Intensive Care Medicine·J G van der HoevenA E Meinders
Jun 1, 1994·Journal of Neurology, Neurosurgery, and Psychiatry·S P GopinathR G Grossman
Oct 1, 1995·Intensive Care Medicine·W HackeS Schwab
Oct 1, 1995·Journal of Neurotrauma·C S RobertsonR K Narayan
Sep 10, 1998·Stroke; a Journal of Cerebral Circulation·S SchwabW Hacke
Dec 4, 1998·Stroke; a Journal of Cerebral Circulation·S SchwabW Hacke

❮ Previous
Next ❯

Citations

Apr 10, 2014·Neurocritical Care·F A ZeilerM West
Jun 15, 2013·Stroke Research and Treatment·Vineeta Singh, Nancy J Edwards
Sep 12, 2014·Neurocritical Care·Mauro OddoUNKNOWN Participants in the International Multidisciplinary Consensus Conference on Multimodality Monitoring
Feb 4, 2006·British Journal of Neurosurgery·J HillmanP Mellergård
Jun 4, 2016·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·David J RohJan Claassen
Apr 18, 2020·Immunological Medicine·Fang He, Yoshinori Matsumoto
Apr 1, 2020·Neurocritical Care·Aaron M CookLori Shutter

❮ Previous
Next ❯

Related Concepts

Related Feeds

Acute Stroke

A stroke occurs when blood supply to the brain is interrupted depriving the brain of oxygen and nutrients. This feed focuses cerebrovascular accidents including ischemic and paralytic stroke.

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.