Jump in the fire - heat shock proteins and their impact on ovarian cancer therapy

Critical Reviews in Oncology/hematology
M B StopeA Mustea

Abstract

Ovarian cancer (OC) is a major problem in gynecological oncology. Options for diagnosis and treatment of advanced stages and thus for patient prognosis have not been improved substantially over the past decades. Heat shock proteins (HSP) are characterized as stress-induced molecular chaperones performing cell survival factor functions. In cancer cells, various crucial and clinically important cell responses are vitally influenced and modulated by HSPs, e.g., cell growth and treatment resistance. Despite the limited knowledge on HSPs in OC progression, their roles as biomarkers, prognostic factors and their drug target properties appears promising for future clinical applications and therapeutic approaches.

References

Aug 11, 1998·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·P AthanassiadouP Athanassiades
Jun 17, 1999·International Journal of Cancer. Journal International Du Cancer·H J ArtsA G Van der Zee
Nov 15, 2002·International Journal of Cancer. Journal International Du Cancer·Irina KorneevaSteven S Witkin
May 14, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Stephen A CannistraLaura King
Aug 12, 2004·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Y TanakaI Kohno
Oct 6, 2005·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Udai BanerjiPaul Workman
Jul 7, 2007·The Journal of Reproduction and Development·Naoki Isobe, Yukinori Yoshimura
Aug 19, 2007·Micron : the International Research and Review Journal for Microscopy·C C JulianiP A Boer
Nov 21, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Stephen A CannistraWilliam McGuire
Jul 30, 2008·Cell Stress & Chaperones·Harm H KampingaLawrence E Hightower
Nov 11, 2008·Reproduction in Domestic Animals = Zuchthygiene·N R SalvettiH H Ortega
Jul 14, 2009·The Oncologist·Susana Banerjee, Martin Gore
Jul 22, 2009·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Mari Bunkholt ElstrandBen Davidson
Sep 12, 2009·Animal Reproduction Science·Melisa M L VelazquezHugo H Ortega
Jul 22, 2010·Molecular Cancer Therapeutics·Maurizio D'Incalci, Carlos M Galmarini
Dec 29, 2010·Cell Stress & Chaperones·Alexander V Sirotkin, Miroslav Bauer
Dec 6, 2011·Reproductive Biology·Melisa M L VelázquezHugo H Ortega
Dec 20, 2011·The Journal of Obstetrics and Gynaecology Research·Eunkuk ParkJong-Phil Chu
Dec 30, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·C Sessa
Dec 24, 2011·International Journal of Clinical Pharmacology and Therapeutics·Matthias B StopeMartin Burchardt
Dec 30, 2011·The New England Journal of Medicine·Timothy J PerrenUNKNOWN ICON7 Investigators
Feb 23, 2013·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Elisabet HjerpeElisabeth Avall-Lundqvist
Aug 1, 2013·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Hanqing LiuDenise C Connolly
Sep 26, 2013·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·M ZhaoQ Chen
Aug 12, 2014·Obstetrics & Gynecology Science·Hye-Ju KangHye-Won Chung

❮ Previous
Next ❯

Citations

Jan 31, 2019·Chemical Biology & Drug Design·Sona TalaeiNosratollah Zarghami
Dec 12, 2018·Current Drug Targets·Vinayak NarayanankuttyAnusree Nair
Dec 20, 2020·Life Sciences·Mahmood BaraniGeorge Z Kyzas
Aug 4, 2021·Seminars in Cancer Biology·Mathilde RegimbeauCarmen Garrido
Mar 31, 2018·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Hassan MellatyarNosratollah Zarghami

❮ Previous
Next ❯

Related Concepts

Related Feeds

Apoptosis in Cancer

Apoptosis is an important mechanism in cancer. By evading apoptosis, tumors can continue to grow without regulation and metastasize systemically. Many therapies are evaluating the use of pro-apoptotic activation to eliminate cancer growth. Here is the latest research on apoptosis in cancer.

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

Related Papers

Annual Review of Cell Biology
C Georgopoulos, W J Welch
Current Medicinal Chemistry
W Hessenkemper, A Baniahmad
Trends in Biochemical Sciences
Stuart K CalderwoodDaniel R Ciocca
Bulletin of the Sloane Hospital for Women in the Columbia-Presbyterian Medical Center, New York City
H C FRICK
© 2021 Meta ULC. All rights reserved