Junctional epidermolysis bullosa in a calf

Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
G X MedeirosS V D Simões

Abstract

A case of epidermolysis bullosa in a calf descendent from a Gir bull and a Gir crossbreed cow is reported. The calf presented with exungulation of all hooves, widespread erosions and crusts on the skin, and ulcers in the oral cavity. Histologically, the skin showed subepidermal separation with clefts occasionally filled with eosinophilic clear fluid, cellular debris, or neutrophils. Ultrastructurally, there was epidermal-dermal separation at the level of the lamina lucida, with the lamina densa attached to the papillary dermis. The hemidesmosomes were poorly defined and small. The clinical, histological, and ultrastructural findings are characteristic of junctional epidermolysis bullosa.

References

Mar 1, 1994·Zentralblatt für Veterinärmedizin. Reihe A·J S Agerholm
Mar 14, 2003·Genetics, Selection, Evolution : GSE·Dragan MilenkovicGérard Guérin
Nov 17, 2009·Journal of Comparative Pathology·A P FosterM J Day

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Citations

Nov 6, 2012·Journal of Comparative Pathology·G X MedeirosA S Borges
Feb 26, 2016·Veterinary Dermatology·Kristin B EdenAline Rodrigues Hoffman
Apr 19, 2015·BMC Veterinary Research·Leonardo MurgianoJørgen S Agerholm
Oct 31, 2014·Veterinary Dermatology·Gildenor X Medeiros, Franklin Riet-Correa
Apr 19, 2015·BMC Veterinary Research·Katia CappelliStefano Capomaccio
Nov 3, 2020·Journal of Veterinary Internal Medicine·Joana G P JacintoJørgen S Agerholm
Aug 31, 2021·Veterinary Record Open·Stefano FrattiniPaola Crepaldi

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Methods Mentioned

BETA
electron microscopy

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