PMID: 11929599Apr 4, 2002Paper

Junctions as organizing centers in epithelial cells? A fly perspective

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Thomas Lecuit, E F Wieschaus

Abstract

Junctions isolate the apical from the basal-lateral surfaces and are required for the polarization of epithelial cells. Genetics of junction formation in Drosophila has identified numerous transmembrane and scaffolding proteins that assemble in membrane-associated complexes. This review focuses on recent findings suggesting that junctions are autonomous organizing centers for the establishment and maintenance of apical-basal polarity in epithelial cells as well as other polarized processes such as the orientation of the division apparatus.

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Citations

Jul 31, 2003·Current Opinion in Genetics & Development·Thomas Lecuit
Apr 2, 2003·Trends in Cell Biology·Mirjam M P ZegersKeith E Mostov
Dec 2, 2009·Proceedings of the National Academy of Sciences of the United States of America·Jennifer ChuaJennifer Lippincott-Schwartz
Oct 15, 2014·The Journal of Cell Biology·Christoph KlingnerRoland Wedlich-Soldner
Oct 22, 2003·Cell Motility and the Cytoskeleton·Mark A Berryman, James R Goldenring
Aug 28, 2010·Fly·Fani Papagiannouli, Bernard M Mechler
Oct 10, 2002·Current Biology : CB·H-Arno J Müller
Apr 22, 2008·Developmental Biology·Midori J SeppaRoss L Cagan
Jun 30, 2016·Nature Reviews. Molecular Cell Biology·Nitya Ramkumar, Buzz Baum
Apr 2, 2003·Nature Cell Biology·Keith MostovMartin ter Beest
Jul 29, 2018·Nature Communications·Pedro Gómez-GálvezLuis M Escudero
Jul 15, 2004·Journal of Cell Science·Thomas Lecuit
Dec 10, 2002·Science·Elisabeth Knust, Olaf Bossinger

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