PMID: 1201597Nov 26, 1975Paper

Junctions in the central nervous system of the cat. IV. Interendothelial junctions of cerebral blood vessels from selected areas of the brain

Cell and Tissue Research
R Dermietzel

Abstract

Interendothelial membrane contacts in different segments of brain blood vessels were investigated by the freeze-etching technique. The study demonstrated that the endothelial cells of the pre- and postcapillary segments were coupled by elaborate zonulae occludentes. These tight junction formations encompassed gap junctions of different sizes and distribution. The globules of the pre- and postcapillary tight junctions revealed a great fragility which led to an atypical distribution of the sealing elements. In the "typical" brain capillaries the endothelial cells were connected by continuous tight junctions. In contrast to the structural continuity of these formations the fenestrated segments of capillaries in the choroid plexus and area postrema demonstrated discontinuous fasciae occludentes. They were composed of rows of individual particles which should be regarded primarily as focal in nature.

Citations

Jan 1, 1980·Archives of Oto-rhino-laryngology·K Jahnke
Jan 1, 1980·Archives of Oto-rhino-laryngology·K Jahnke
Jan 1, 1988·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·J H Tao-Cheng, M W Brightman
Feb 1, 1992·Developmental Dynamics : an Official Publication of the American Association of Anatomists·R DermietzelB Stevenson
Mar 19, 2014·FEBS Letters·Marijke De BockLuc Leybaert
Jul 24, 2007·American Journal of Physiology. Lung Cellular and Molecular Physiology·Sanda A PredescuAsrar B Malik
Aug 3, 2002·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Markus RamsauerRolf Dermietzel

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