Just one look, and fractures and death can be predicted in elderly ambulatory women

Gerontology
Paul GerdhemKarl J Obrant

Abstract

The chronological age is clearly the strongest risk factor for fractures or death. Age as a concept can be described exactly as chronological age. Age in relative terms can be described as biological age. We postulated that, even without taking into account known or unknown comorbidity, an immediate and totally subjective evaluation of an individual's biological age is predictive of forthcoming fractures and death. At baseline the biological age was estimated in 1,004 randomly recruited ambulatory 75-year-old women. All women were of the same ethnic background. Two independent observers estimated the biological age within 15 s of first sight of each woman. Based on this estimation of the biological age, the women were divided into tertiles. The women were then followed prospectively for a mean of 4.6 (range 3.0-6.5) years. All retrospective fractures and prospective fractures and deaths were registered. When the tertile of the biologically oldest women was compared with all other women, their odds ratio for sustaining any type of prospective fracture was 1.71 (95% confidence interval 1.22-2.39), for hip fractures 2.69 (1.42-5.11), for clinical vertebral fractures 2.83 (1.57-5.11), and for multiple fractures 3.17 (1.64-6.10). Al...Continue Reading

Citations

Feb 23, 2013·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·O J de VriesD J H Deeg
Mar 5, 2010·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Fiona McGuiganKristina Akesson
Feb 19, 2019·Geriatric Orthopaedic Surgery & Rehabilitation·Jennifer M T A MeessenRob G H H Nelissen
Jan 10, 2021·Current Osteoporosis Reports·Kristina E Åkesson, Fiona E A McGuigan
Feb 19, 2021·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Cecilia RogmarkViktor Hamrefors
Dec 12, 2017·Best Practice & Research. Clinical Rheumatology·Fiona E McGuiganKristina E Åkesson

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