PMID: 6975422Jul 25, 1981Paper

Juvenile chronic arthritis

The Medical Journal of Australia
P McDougal, D J Hill

Abstract

A review of the clinical and immunological features of 72 children with chronic arthritis revealed a similar pattern of disease in Australian children when compared with overseas studies. Most of the children had pauciarticular disease, but polyarthritis and systemic forms were seen. Although HLA=B27 was identified in some patients, no florid example of ankylosing spondylitis in childhood was seen. A small, but significant, number of children had evidence of potentially blinding iritis which developed insidiously, and one child had acute uveitis. Although elevated antistreptolysin-O titres and raised total IgM levels were seen in a significant number of children, they were not confined to any particular clinical pattern and were not of any major prognostic value. Half the children were severely incapacitated at the height of their disease, but follow-up for periods of up to five years revealed that fewer than 5% had a significant permanent disability.

References

Jun 18, 1977·The Medical Journal of Australia·D BarracloughJ S Percy
Apr 1, 1978·Annals of the Rheumatic Diseases·B M Ansell
May 7, 1977·The Medical Journal of Australia·D Barraclough, A S Russell
Jun 1, 1976·Annals of the Rheumatic Diseases·H F HillJ G Bodmer
Apr 28, 1973·Lancet·D A BrewertonR D Sturrock
Aug 1, 1973·The Journal of Clinical Investigation·J T CassidyD B Sullivan
Apr 5, 1973·The New England Journal of Medicine·L SchlossteinC M Pearson
Sep 28, 1967·The New England Journal of Medicine·J J Calabro, J M Marchesano
Jun 25, 1949·Journal of the American Medical Association·O STEINBROCKERR C BATTERMAN

❮ Previous
Next ❯

Citations

Jun 1, 1987·Australian and New Zealand Journal of Medicine·N W McGill, P J Gow
Jan 1, 1994·Rheumatology International·A Aggarwal, R Misra
May 1, 1996·Indian Journal of Pediatrics·A Aggarwal, R N Misra

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.