Juvenile granulosa cell ovarian tumor: clinicopathological evaluation of ten patients

Journal of the Turkish German Gynecological Association
Alper KaralokGökhan Tulunay

Abstract

We aimed to analyze the clinical characteristics and management of ten patients who were diagnosed with juvenile granulosa cell ovarian tumor (JGCOT). The records of 10 patients diagnosed with JGCOT between April 1995 and January 2014 in the Gynecological Oncology Clinic of our institution were retrospectively evaluated. The median age of the patients was 21.5 years (range; 13-36). Nine patients had stage IA disease and one had stage IC disease according to the International Federation of Gynecology and Obstetrics (FIGO) criteria. Five patients underwent pelvic and para-aortic lymph node dissection. None of them had lymph node involvement. All but two patients underwent unilateral salpingo-oophorectomy. One of the other two patients had cystectomy and the other had total abdominal hysterectomy and bilateral salpingo-oophorectomy. Three patients had adjuvant therapy after surgery. Two of these patients took chemotherapy and the other took radiotherapy. Four of the five patients who desired pregnancy achieved five term pregnancies. The median follow-up time of the patients was 58 months (range; 3-113). No recurrence was observed in the follow up period. JGCOT generally occurs during childhood. The primary management of JGCOT is t...Continue Reading

Citations

Apr 16, 2016·Gynecologic Oncology·William D FoulkesW Glenn McCluggage
Oct 6, 2016·Journal of Pediatric and Adolescent Gynecology·Hao WuRajkumar Venkatramani
Jun 21, 2020·American Journal of Clinical Pathology·Yuhong YeShie Wang
Feb 8, 2019·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Dan ZhaoBin Li
Feb 16, 2021·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Alice BergaminiGiorgia Mangili
Feb 24, 2021·Pediatric Hematology and Oncology·İdil Rana UserSaniye Ekinci
Mar 17, 2021·Annals of Diagnostic Pathology·Gupta ParikshaaSrinivasan Radhika
May 25, 2021·Acta Obstetricia Et Gynecologica Scandinavica·Junting LiBeihua Kong
Oct 26, 2021·Archives of Gynecology and Obstetrics·Elijah NdhlovuBiao Chen

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