Juvenile hormone acid: evidence for a hormonal function in induction of vitellogenin in larvae of Manduca sexta

Archives of Insect Biochemistry and Physiology
S M. IsmailG Bhaskaran

Abstract

In the tobacco hornworm (Manduca sexta), vitellogenin (Vg), the major yolk protein precursor, and its mRNA are first detectable in the prepupal stage; and production of both can be enhanced by methoprene, a juvenile hormone (JH) analog. Competence to respond to methoprene is acquired after ecdysteroid-initiated commitment for metamorphosis. Here we show that acquisition of competence requires prior exposure to JH-II acid in addition to ecdysteroid. Application of 20-hydroxyecdysone or RH5992, an ecdysteroid analog, to isolated abdomens from feeding larvae (precommitment) results in exposure of the dorsal vessel (EDV), a sign of metamorphic commitment--but such abdomens do not make Vg in response to methoprene. However, injection of JH-II acid along with 20-hydroxyecdysone into isolated abdomens causes Vg production in response to methoprene. Methoprene acid similarly induces competence to respond to methoprene. Northern blot analysis confirmed that Vg transcripts are present in fat body only if isolated abdomens were pretreated with both ecdysteroid, and JH-II acid or methoprene acid. The latter two can induce competence even in precocious prepupae resulting from removal of the corpora allata (the glands that produce JH) from e...Continue Reading

References

Jan 1, 1979·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·D GieseckeM Stangassinger
Apr 1, 1990·General and Comparative Endocrinology·G BhaskaranM Muszynska-Pytel
Jun 1, 1974·The Biological Bulletin·M M Nijhout, L M Riddiford
Jul 1, 1981·General and Comparative Endocrinology·W E BollenbacherL I Gilbert
Sep 1, 1980·General and Comparative Endocrinology·G BhaskaranH Röller
Jun 20, 1995·Proceedings of the National Academy of Sciences of the United States of America·M A HarmonD J Mangelsdorf
Feb 12, 1998·Proceedings of the National Academy of Sciences of the United States of America·G Jones, P A Sharp
Dec 1, 1977·Wilhelm Roux's Archives of Developmental Biology·Margery J Fain, Lynn M Riddiford

❮ Previous
Next ❯

Citations

Mar 8, 2005·Journal of Insect Physiology·Michelle Pellissier ScottKaren L Carleton
Jun 14, 2000·Insect Biochemistry and Molecular Biology·B A ThomasB D Hammock
Jul 6, 2000·Insect Biochemistry and Molecular Biology·K G Davey
Sep 16, 2000·Insect Biochemistry and Molecular Biology·K D BakerD J Mangelsdorf
Nov 24, 2001·Insect Biochemistry and Molecular Biology·G JonesD Jones
Nov 24, 2001·Insect Biochemistry and Molecular Biology·A C Hinton, B D Hammock
Mar 1, 2003·Insect Biochemistry and Molecular Biology·A C Hinton, B D Hammock
Sep 18, 2004·Insect Molecular Biology·A R BarchukZ L P Simões
Dec 1, 2001·Annual Review of Entomology·James W Truman, Lynn M Riddiford
Sep 19, 2000·Bioscience, Biotechnology, and Biochemistry·T ShiotsukiB D Hammock
Aug 31, 2010·Journal of Pesticide Science·Shizuo G Kamita, Bruce D Hammock
Jul 28, 2004·Proceedings of the National Academy of Sciences of the United States of America·Gro V AmdamRobert E Page
Jun 4, 2008·Journal of Insect Physiology·Christa SchafellnerFrantisek Sehnal
Oct 6, 2005·Insect Biochemistry and Molecular Biology·Sheng LiDavid A Schooley
Jul 19, 2002·Archives of Insect Biochemistry and Physiology·Katherine C L KeiserNancy Wisnewski
Oct 24, 2020·Insect Biochemistry and Molecular Biology·Xiaolong CaoHaobo Jiang
Jun 29, 2000·Biochemical and Biophysical Research Communications·K Kadono-OkudaG Jones
Jul 6, 2000·Insect Biochemistry and Molecular Biology·L I GilbertR M Roe
Feb 1, 2005·Insect Biochemistry and Molecular Biology·Qi-Rui ZhangSheng Li
May 23, 2007·Insect Biochemistry and Molecular Biology·Erica J CroneJohn G Oakeshott

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.