Juvenile xanthogranuloma occurring in the oral cavity: case report and histopathological findings

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
S KawashiriK Imai

Abstract

Juvenile xanthogranuloma is commonly seen in the dermis, and only very rarely develops in the oral mucosa. Here were report a case that occurred in the anterior palate of a 9-year-old boy. The lesion appeared as a dark red and well-defined nodule measuring 12 x 14 mm. Histologically, it consisted of a proliferation of histiocytes and fibroblastic stroma intermingled with foamy cells. Many lipid droplets without limiting membrane were observed in the cytoplasm under electron microscopy, but no Langerhans' cell granules were observed. The proliferative histiocytes were positive for lysozyme and macrophage HAM56 under immunohistochemical observation, but not for S-100 protein. From these findings, the lesion was diagnosed as juvenile xanthogranuloma. The post-operative course, now amounting to 7 years, has been uneventful.

References

Aug 1, 1987·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·J PalaciosF Contreras
Sep 1, 1974·Oral Surgery, Oral Medicine, and Oral Pathology·A Kjaerkeim, T Stokke
May 1, 1980·The Annals of Otology, Rhinology, and Laryngology·R H OssoffG F Tucker
Nov 1, 1981·Oral Surgery, Oral Medicine, and Oral Pathology·D M CohenA S Miller
Aug 1, 1993·Journal of the American Academy of Dermatology·K F HelmJ G Marks
Feb 1, 1994·The American Journal of Surgical Pathology·B ZelgerE Wilson-Jones
Oct 1, 1996·The American Journal of Dermatopathology·B W ZelgerR Cerio

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Citations

Sep 27, 2002·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Catherine FlaitzJohn Hicks
Jan 26, 2011·Journal of Medical Case Reports·Alessandro VillaFrancesco Villa
Jan 14, 2009·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Alberto ConsolaroCarlos Eduardo Bacchi
Jun 10, 2000·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·T ShimoyamaF Ide
Apr 12, 2001·The British Journal of Dermatology·G Fabrizi, G Massi
Apr 7, 2018·Journal of Cutaneous Pathology·Celeste Sánchez-RomeroEvangelina Gutiérrez Cortés

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