Keeping babies warm: a non-inferiority trial of a conductive thermal mattress

Archives of Disease in Childhood. Fetal and Neonatal Edition
Swarna R BhatVinod K Bhutani

Abstract

External thermal support is critical for preterm or ill infants due to altered thermoregulation. Incubators are the gold standard for long-term support and have been adopted successfully in many countries. Alternatives such as radiant warmers, blankets and others are often used as standard of care (SoC) in resource-limited settings when infants are otherwise not in Kangaroo Mother Care (KMC). In this pilot study, we evaluate the feasibility of a conductive thermal mattress (CTM) using phase change materials as a low-cost warmer. We conducted a prospective multicentre open-label randomised controlled trial to determine non-inferiority of this CTM to SoC warming practices in low birthweight infants. The primary outcome was maintenance of axillary temperature. We equally randomised 160 infants to CTM or SoC. The latter cohort continued to receive warmth by radiant warmers (n=48), blankets (n=18), warmed cradles (n=7) or KMC (n=7) before, during and subsequent to the study. CTM was deemed non-inferior since warmed babies had higher axillary temperature compared with SoC (mean increase 0.11±0.03°C SEM; p<0.001). Post hoc comparison to radiant warmers alone showed that CTM led to a higher axillary temperature (mean increase by 0.14±0...Continue Reading

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Citations

Mar 18, 2015·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Mehmet Yekta OncelUgur Dilmen
Mar 6, 2016·Archives of Disease in Childhood. Fetal and Neonatal Edition·N Karthik Nagesh, Abdul Razak
Dec 21, 2017·BMC Pregnancy and Childbirth·Karsten LunzeDavid E Bloom
Jul 29, 2018·Journal of Perinatology : Official Journal of the California Perinatal Association·Machilakath Panangandi ShabeerNiranjan Thomas
Jul 21, 2020·Journal of Perinatology : Official Journal of the California Perinatal Association·Vallaree Anant MorgaonkarSomashekhar Marutirao Nimbalkar
Nov 7, 2019·Global Pediatric Health·Leana MayAnne Hansen
Feb 13, 2018·The Cochrane Database of Systematic Reviews·Emma M McCallLinda Johnston
Dec 6, 2020·Advances in Neonatal Care : Official Journal of the National Association of Neonatal Nurses·Kristi Lynn DixonJulie Thompson

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