PMID: 6170266Jan 1, 1981Paper

Keratin polypeptide modifications induced by human papilloma viruses (HPV)

Archives of Dermatological Research
M J StaquetJ Thivolet

Abstract

The keratin polypeptide composition of different types of warts was studied by means of SDS polyacrylamide gel electrophoresis. It was composed of five main polypeptides, similar to those found in normal epidermis (mol. wt. 67K to 55K) and an additional polypeptide (72K) was often detected. The distribution of each polypeptide was expressed as percentage of total keratins in the different samples. The most characteristic feature observed in warts was the marked decrease of the 67K polypeptide. There were increased amounts of the 67K-63K proteins and some difference was observed in the distribution of these proteins in the different types of warts. Thus, the viral infection seems mainly to modify the proteins which are only involved in the latest stages of the differentiation of keratinocytes.

References

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Citations

Jan 1, 1984·Archives of Dermatological Research·Y ChardonnetJ Thivolet
Jan 1, 1982·Archives of Dermatological Research·J ViacJ Thivolet
Jan 1, 1987·Virchows Archiv. A, Pathological Anatomy and Histopathology·R P HenkeH S Koppang
Jan 1, 1988·Virchows Archiv. A, Pathological Anatomy and Histopathology·D BroekaertE Gillis
Feb 1, 1982·Journal of the American Academy of Dermatology·C M Lapiere
Oct 1, 1992·Journal of Cutaneous Pathology·M NindlY Ishibashi
Jan 1, 1991·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·J KellokoskiK Syrjänen
May 1, 1991·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·L N NielsenB Norrild
Apr 1, 1984·Journal of Oral Pathology·T LöningJ Thivolet
Jan 1, 1986·Journal of Oral Pathology·H ClausenE Dabelsteen
Oct 24, 2007·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Constantino Ledesma-MontesJuan Carlos Hernández-Guerrero
Jul 1, 1983·The Journal of Investigative Dermatology·T T SunJ Woodcock-Mitchell

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