PMID: 11488708Aug 8, 2001Paper

Keratoacanthoma with perineural invasion: a report of 40 cases

The Australasian Journal of Dermatology
A M GodboltDavid Weedon


Keratoacanthoma is a unique clinicopathological entity, despite a recent trend to regard it as a variant of squamous cell carcinoma. The occurrence of perineural invasion is an uncommon phenomenon in keratoacanthomas, with a predilection for lesions on the face. We studied a series of 40 cases of keratoacanthoma in which perineural invasion occurred. Of the 40 cases, 27 were from the head or neck region. We found no metastasis or direct death attributable to the presence of perineural invasion in the 35 cases in our series for whom follow-up data were available. In only one case did local recurrence occur and this was not considered by the authors to be directly attributable to the presence of perineural invasion. These findings add further support to the notion that keratoacanthoma is biologically different from squamous cell carcinoma.


Jul 1, 1979·Pathology·David Weedon, G Ritchie
Dec 1, 1977·Journal of Cutaneous Pathology·I P JaneckaB Cosman
Oct 1, 1992·The American Journal of Dermatopathology·E Calonje, E W Jones
Jan 1, 1992·Journal of the American Academy of Dermatology·R E KwaR L Moy
Oct 1, 1984·American Journal of Surgery·H GoepfertM D Luna
Aug 1, 1993·The American Journal of Dermatopathology·E HodakA B Ackerman
Jan 1, 1994·Journal of the American Academy of Dermatology·R A Schwartz


Jul 18, 2003·Ophthalmology·Mark J DonaldsonRichard Williamson
Apr 6, 2004·Facial Plastic Surgery Clinics of North America·Christie T AmmiratiGeorge J Hruza
Jul 27, 2010·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Matthew PetrieCarmen Campanelli
Aug 23, 2005·The British Journal of Ophthalmology·I LeibovitchD Selva
Jun 21, 2013·Dermatology Practical & Conceptual·Philipp TschandlDavid Weedon
Nov 21, 2008·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·David E GeistGary S Rogers
Feb 12, 2004·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Robert A Schwartz
Feb 9, 2016·Journal of the American Academy of Dermatology·Bartlomiej Kwiek, Robert A Schwartz
Oct 22, 2011·Clinics in Dermatology·Jennifer L DePryJerry D Brewer
Jun 15, 2010·Clinics in Dermatology·Christine J Ko
Dec 17, 2008·The British Journal of Oral & Maxillofacial Surgery·I Al-HadadK Webster
May 30, 2009·Journal of Cutaneous Pathology·Ehab A Husain, Wael I Al-Daraji
May 1, 2008·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Yasmin BasogluSonja Ständer
Jun 26, 2010·ANZ Journal of Surgery·David WeedonRichard Williamson
Nov 18, 2010·Pathology·David WeedonRichard Williamson
Feb 14, 2015·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Seong H RaScott W Binder
Aug 1, 2015·Archives of Craniofacial Surgery·Hyochun ParkHyeonjung Yeo
Apr 24, 2010·The American Journal of Dermatopathology·David WeedonRichard Williamson
Oct 3, 2006·The American Journal of Dermatopathology·Trevor W Beer
Mar 25, 2008·The American Journal of Dermatopathology·Steven KossardCarolyn Choy
Aug 21, 2003·Eye·E H HughesD M Tole
Dec 25, 2013·The American Journal of Dermatopathology·Jacqueline A Savage, John C Maize
Apr 13, 2019·Head and Neck Pathology·Efthimios SivridisAlexandra Giatromanolaki
Oct 15, 2013·Journal of Cutaneous Pathology·David Weedon, Cliff Rosendahl
Nov 29, 2013·International Journal of Surgical Pathology·Phyu P AungMeera Mahalingam
Feb 10, 2017·Advances in Anatomic Pathology·Mansour MoghimiAmir Aryanfar

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