Keratoconus associated with cone-rod dystrophy: a case report

Cornea
Rajesh Fogla, Geetha K Iyer

Abstract

A 31-year-old man with bilateral keratoconus associated with apical corneal scarring underwent uneventful penetrating keratoplasty in his left eye. Postoperatively his best-corrected visual acuity did not improve beyond 20/120. Examination of the fundus revealed features suggestive of bull's eye maculopathy. On performing an electroretinogram study of both eyes, grossly delayed implicit time with reduced amplitudes of the rod response and extinguished cone waveforms were noted, indicating cone-rod dystrophy. Color blindness was also noted on testing with Ishihara's pseudoisochromatic plates. Genetic counseling showed this to be an isolated defect with negative family history. Preoperative electrophysiologic studies may have a prognostic role in these cases.

References

Jan 1, 1973·Clinical Genetics·D A Leighton, R Harris
Jan 1, 1995·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·K R Wilhelmus
Sep 1, 1996·Cornea·M MoschosM Tsalouki

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Citations

Apr 30, 2011·Comparative and Functional Genomics·Ma MingxiaoLi Pengfei
Feb 23, 2010·Journal of Medical Case Reports·Joo Youn Oh, Hyeong Gon Yu
Sep 18, 2018·Ophthalmic Surgery, Lasers & Imaging Retina·Serkan Akkaya
Nov 20, 2009·European Journal of Ophthalmology·Enzo Maria VingoloRoberto Grenga

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