Abstract
Increasing evidence suggests that keratoconus may have an inflammatory component. The possible association of keratoconus with inflammatory bowel disease (IBD) has yet to be determined. The aim of this study was to determine the prevalence of keratoconus and suspect keratoconus in patients with IBD. All consecutive adult IBD patients seen in the Department of Gastroenterology, Nancy, University Hospital, France, between March 2014 and June 2014 were included. Pregnant women, rigid lens wearers, patients with a family history of keratoconus and patients with a history of refractive surgery were excluded. A control group of healthy subjects was included. All included patients underwent a corneal topography (OPD-Scan III, Nidek) to detect keratoconus or suspect keratoconus. Rabinowitz videokeratographic indices were the basis of corneal topography interpretation. Two hundred and one IBD patients were included, 150 with Crohn's disease and 51 with ulcerative colitis. Mean age was 38.7 years and 121 were women. Mean disease duration was 10.8 years. Two IBD patients were diagnosed with keratoconus (1%) and 38 with suspect keratoconus (18.9%). Overall prevalence of keratoconus and suspect keratoconus was 19.9% (95% confidence interval...Continue Reading
References
Mar 15, 1986·American Journal of Ophthalmology·R H KennedyJ A Dyer
Jan 1, 1984·Survey of Ophthalmology·J H KrachmerM W Belin
Feb 1, 1984·Ophthalmology·D L KnoxE Mustonen
Jul 1, 1995·Archives of Ophthalmology·N MaedaM K Smolek
Mar 11, 1998·Survey of Ophthalmology·Y S Rabinowitz
Oct 8, 1999·Journal of Cataract and Refractive Surgery·Y S Rabinowitz, K Rasheed
Nov 12, 2003·Survey of Ophthalmology·Faruque D Ghanchi, Bjorn J Rembacken
May 4, 2004·Ophthalmology·David LevyFrancois Malecaze
Jul 17, 2004·Cornea·David VarssanoRossen Hazarbassanov
Apr 6, 2005·Ophthalmology·Isabel Lema, Juan A Durán
Jul 8, 2008·Lancet·Laurent Peyrin-BirouletJean-Frédéric Colombel
Sep 25, 2008·Journal of Refractive Surgery·Eberhard SpoerlLutz E Pillunat
Mar 24, 2009·The British Journal of Ophthalmology·I LemaE Díez-Feijoo
Jun 26, 2009·The British Journal of Ophthalmology·Stephen D Klyce
Aug 31, 2010·Cornea·Arie Y NemetIgor Kaiserman
Feb 8, 2011·PloS One·Albert S JunShukti Chakravarti
Nov 16, 2012·Clinical Ophthalmology·Leopoldo SpadeaCharles Wm Stewart
Nov 28, 2012·Nutrition Research·Sun Jin HurJae Dong Lee
Jul 24, 2013·Inflammation & Allergy Drug Targets·Durgaprasad LavetiRavinder Nagpal
Aug 6, 2013·Journal français d'ophtalmologie·P FourniéF Malecaze
Jan 25, 2014·Cornea·Johnson C H TanSonia N Yeung
Sep 19, 2014·World Journal of Gastroenterology : WJG·Claudia OttMartina Müller
Jan 7, 2015·World Journal of Gastroenterology : WJG·Lin-Jing LiBai-Sui Feng
Citations
Jun 29, 2016·Eye and Vision·Yelena BykhovskayaYaron S Rabinowitz
Aug 4, 2018·Investigative Ophthalmology & Visual Science·Daizong WenJinhai Huang
Aug 1, 2020·Case Reports in Ophthalmological Medicine·Anastasia TsiogkaGeorge L Spaeth
Jun 8, 2017·International Ophthalmology Clinics·Katherine J Davis, Shahzad I Mian
Feb 18, 2021·Korean Journal of Ophthalmology : KJO·Jee-Won MokChoun-Ki Joo