Key molecules involved in receptor-mediated lymphocyte activation

Current Protocols in Immunology
John J O'SheaL E Samelson

Abstract

This unit, along with Unit 11.9B, provides a summary of our current knowledge about various signaling pathways critical to the function of immune cells. Here, our understanding of T cell receptor (TCR)- and B cell receptor (BCR)-mediated signaling is summarized. A schematic representation of immunologically relevant cytokine receptors and the Janus Family Kinases (JAKs) that is activated through these receptors is provided, along with details about molecules involved in interleukin 2 mediated signal transduction.

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Citations

Jan 9, 2013·The Journal of Immunology : Official Journal of the American Association of Immunologists·Nobuaki KobayashiHidekazu Shirota

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