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Key role of amino acid repeat expansions in the functional diversification of duplicated transcription factors

bioRxiv

Feb 5, 2015

Núria Radó-TrillaM. Mar Alba

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Abstract

The high regulatory complexity of vertebrates has been related to two closely spaced whole genome duplications (2R-WGD) that occurred before the divergence of the major vertebrate groups. Following these events, many developmental transcription factors (TFs) were retained in multiple co...read more

Mentioned in this Paper

LHX2 wt Allele
Interleukin 2 Receptor
Amino Acid [EPC]
PHOX2B gene
Complex (molecular entity)
Vincristine
PHOX2A gene
Vertebrates
LHX9 gene
LHX2 protein, human
19
1
3
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  • Key role of amino acid repeat expansions in the functional diversification of duplicated transcription factors

    bioRxiv

    Feb 5, 2015

    Núria Radó-TrillaM. Mar Alba

    PMID: 990014910

    DOI: 10.1101/014910

    Abstract

    The high regulatory complexity of vertebrates has been related to two closely spaced whole genome duplications (2R-WGD) that occurred before the divergence of the major vertebrate groups. Following these events, many developmental transcription factors (TFs) were retained in multiple co...read more

    Mentioned in this Paper

    LHX2 wt Allele
    Interleukin 2 Receptor
    Amino Acid [EPC]
    PHOX2B gene
    Complex (molecular entity)
    19
    1
    3

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