PMID: 7766749Feb 1, 1995Paper

Khat chewing delays gastric emptying of a semi-solid meal

Alimentary Pharmacology & Therapeutics
T D HeymannI M Murray-Lyon


The leaves of Khat are chewed for their central stimulant effect, but their use may cause anorexia and constipation. Gastric emptying of a radio-labelled semi-solid meal was measured in 12 healthy volunteers on two occasions a week apart. Subjects chewed either Khat leaves (Catha edulis) or lettuce for 2 h before the study. Gastric emptying was significantly (P < 0.02) prolonged after chewing Khat compared with lettuce. The sympathomimetic action of cathinone in Khat may cause the observed delay in gastric emptying.


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